For mRNA, Covid Vaccines Are Just the Beginning | |
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Anonymous Coward User ID: 84616873 United States 11/05/2022 04:20 PM Report Abusive Post Report Copyright Violation | For mRNA, Covid Vaccines Are Just the Beginning With clinical vaccine trials for everything from HIV to Zika, messenger RNA could transform medicine—or widen health care inequalities. [link to www.wired.com (secure)] KATALIN KARIKÓ NEVER intended to make vaccines. For years before the pandemic, the Hungarian-American biochemist had been working to realize the therapeutic potential of mRNA—first trying to create a synthetic version of the messenger molecule that wouldn’t trigger the body’s inflammatory response, and then, once she and colleague Drew Weissman had achieved that goal, trying to get the medical and scientific community to pay attention. She had envisioned the technology being used to treat those recovering from heart attacks and strokes. But it was the frantic race for a Covid vaccine that earned Karikó belated global recognition. The work she and her colleagues had done on mRNA provided the foundation for Moderna and BioNTech to quickly develop Covid vaccines that have now saved millions of lives. Traditional vaccines train the immune system by introducing it to harmless versions of whole viruses—the body learns to recognize the virus’s key features, such as SARS-CoV-2’s infamous spike protein. These new mRNA vaccines found a more elegant way to achieve the same goal, using messenger RNA—a genetic molecule found throughout nature that’s used to transmit information within and between cells—to provide the body with a set of instructions on how to make the spike protein itself, essentially borrowing the body’s internal machinery and turning it into a photocopier. This difference allowed mRNA vaccines to be designed, created, and approved in record time. Over the past 18 months, mRNA technology has been injected into billions of arms and has helped slow the devastating impact of the pandemic. But its long-term impact—accelerated by Covid—could be even greater. “It seems like the sky is the limit,” says Karikó. “Previously the belief was not there.” Dozens of clinical trials are now underway for new forms of the mRNA vaccine—targeting everything from malaria to Zika, herpes, and cytomegalovirus. Last month, Moderna—which was founded in 2014 to explore the potential of mRNA—announced it had started Phase I clinical trials for two mRNA-based HIV vaccines. “The timeline for what can be achieved using the mRNA platform is so much better,” says Carl Dieffenbach, director of the Division of AIDS at the US National Institutes of Health, who is overseeing those trials. There was some work on mRNA happening before the pandemic—Moderna had spent years on the lipid envelope that encases the strand of mRNA in the vaccine, for instance. “Like all overnight successes, mRNA has been in development for a long time,” says Richard Hatchett of the Coalition for Epidemic Preparedness Innovations (CEPI). The US Biomedical Advanced Research and Development Authority invested in an mRNA vaccine for Zika in 2016, but “the urgency sort of trailed off” as the outbreak subsided, Hatchett says. There had also been tentative attempts to develop mRNA platforms for other coronaviruses, such as MERS, work that proved crucial when Covid broke out. Moderna was able to tweak its MERS vaccine for the new disease, meaning its Covid vaccine entered clinical trials just 66 days after SARS-CoV-2’s genetic sequence was published. It’s true that mRNA vaccines would probably have come to market eventually, but they were on what Dieffenbach calls “a leisurely stroll.” Covid “pressure-tested” them—advancing their emergence by years or decades. Karikó remembers organizing the first mRNA conference in 2013 and says that nobody in attendance would have expected an FDA-approved product less than 10 years later. “Because of the success against Covid, we’re going to see tremendous investment, and we’re going to learn just how flexible it is and how finely we can target,” says Hatchett. One of mRNA’s strengths is its “remarkable agility,” as Hatchett puts it. Its only raw ingredients are the four nucleotides that form the “letters” of the RNA sequence, so it can be designed and made pretty rapidly. “Biological manufacturing is very hard and temperamental and has been difficult to introduce in many environments. It’s taken India decades to build up the vaccine manufacturing capability they have,” says Hatchett. “It may be easier for countries to develop an mRNA production capacity than traditional biological manufacturing capability.” Developing countries could, Hatchett suggests, leapfrog over traditional vaccine-manufacturing processes and go straight to mRNA—mRNA plants are already being planned in countries across Africa and Asia. After Covid, they could be quickly repurposed to create vaccines for other diseases—all you need to do is change the order of the bases in the mRNA to give the body a new set of instructions. There are also far fewer concerns about purity or contamination than with traditional vaccines—the body quickly translates, expresses, and breaks down the strand of mRNA. “mRNA is completely interchangeable,” says Jackie Miller, senior vice president for infectious diseases at Moderna. “What changes between the different vaccines is the DNA template that we utilize to synthesize the messenger RNA, but across all of our vaccine portfolio, we’re using the same lipid nanoparticle.” [@50% MORE AT LINK] [link to www.wired.com (secure)] I guess they really want to make everyone anti-vaxxers. |
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hankie
Everything User ID: 80628258 United States 11/05/2022 04:34 PM Report Abusive Post Report Copyright Violation | will never take a vaccine of any kind ever again Quoting: Anonymous Coward 18739626 fuck the medical establishment to hell Ditto Who the fuck would trust these psychopaths ever again? I really agree with your assessment that they are psychopaths. What makes it worse is they are rich psychopaths with power. Sorry I got a headache These are the times that tries men's and women's souls! May we come though it victorious! |
Anonymous Coward User ID: 84638619 United States 11/05/2022 04:39 PM Report Abusive Post Report Copyright Violation | will never take a vaccine of any kind ever again Quoting: Anonymous Coward 18739626 fuck the medical establishment to hell Ditto Who the fuck would trust these psychopaths ever again? I really agree with your assessment that they are psychopaths. What makes it worse is they are rich psychopaths with power. Hankie mRNA and DNA healing have been given to this world for a purpose and its holy... Its time to stop being copy cat. |
hankie
Everything User ID: 80628258 United States 11/05/2022 05:00 PM Report Abusive Post Report Copyright Violation | will never take a vaccine of any kind ever again Quoting: Anonymous Coward 18739626 fuck the medical establishment to hell AGREED! After all that has happened, I don't trust ANY more injections of any sort. I going to go with what God said, I created the herbs of the fields for curing the nations. Health by the plants and other green things growing, that are herbs. I think the cancer Australians who work in research of this very thing said so far, the plant they found cures cancer. This you can thank a Lion with cancer who escaped and they could find him, but he came back, they thought he was dead because of cancer. He was healthy when he came back, with no cancer at all. This was years ago and they had been searching for that plant, it was found I guess for some time now to have gotten so far into the research properties, curing cancer with an herb of the fields. And they say the bible isn't about real things. This has been done in the past, and lack of vitamin C caused Scurvy, lemons, oranges, and limes cure them of Scurvy. There are other plants that cure, not treat diseases. You know that doctors before they brought in pharmaceutical medicines used plant base medicine and different mineral compounds to treat and cure people. There were a few other things they used but mostly it was plant base and mineral compounds they formulated themselves. They are not teaching the same as they did, or more doctors would treat their patients in the old ways, they changed the teaching of doctors to just do the Pharma way. They made laws against painkillers, one was used and I used it for pain when I was younger and was based on partly opium, I never got addicted to it for sure, it tasted horrible. At the start Coke Cola had cocaine in it, men and women at the end of a work day would drink one coke and their bodies would relax from the strain of working manually. The government made them remove it. People didn't abuse it, they drank one coke, that is it. It is strange isn't it, now people abuse it. Sorry I got a headache These are the times that tries men's and women's souls! May we come though it victorious! |
TerraFirma's Esoterrorist
User ID: 83924675 United States 11/05/2022 05:10 PM Report Abusive Post Report Copyright Violation | Thread: BOMBSHELL: MAN in 2013 TRIAL WITH 200K PEOPLE TO TEST MRNA-BASED MEDICATION, less than 5 alive! The takeway: Quoting: TerraFirma's Esoterrorist COVID illness (exposure to SARS-COV-2 bioweapon) is 99.99% Non Fatal. COVID mRNA "Investigative" injections are 99.99% Fatal ...within 9 years. www.bitchute.com/video/rZec9bjNmgFl/ Last Edited by TerraFirma's Esoterrorist on 11/05/2022 05:11 PM "Keep a weather eye to the chart on high and go home another way" –James Taylor Never Die Young |
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Loup Garou
User ID: 80950725 United States 11/05/2022 06:23 PM Report Abusive Post Report Copyright Violation | The novel coronavirus disease (COVID-19) is caused by a virus (SARS-Cov-2) ... just the facts a common cold. Just because YOU don’t believe in the Rougarou; or the Loup Garou, don’t make you safe; No ! The Constitution is a blend of 'moral certitude' -- which is one of the reasons that criminals are determined to be rid of it and We the People must be even more determined to defend it. "If there must be trouble, let it be in my day, that my child may have peace." - Thomas Paine The only thing the Illuminati fears is an independent person who can live, eat, sleep, stay warm and defend themselves separate from Federal help. Pray that the Lord gives us more time! The End is near and time is short! A fool takes no pleasure in understanding, but only in expressing his opinion. ~Proverbs 18:2 For those who understand, no explanation is needed. For those who do not understand, no explanation is possible "A candle loses nothing by lighting another candle" - James Keller Checkd, Keked, and Rekt! #Kids2 |
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No holds barred
User ID: 84519337 Mexico 11/05/2022 06:28 PM Report Abusive Post Report Copyright Violation | the sky is the limit, that is there philosophy, |
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Anonymous Coward User ID: 84011718 Luxembourg 11/05/2022 06:51 PM Report Abusive Post Report Copyright Violation | mRNA has potential for future treatments of things like cancer. Imagine creating mRNA that can cause cancer cells and only cancer cells to self destruct? That would be a lot safer than chemo Quoting: Anonymous Coward 84599932 potential for EVIL is far to great Where Fauci. What's he up to? |
Anonymous Coward (OP) User ID: 84645381 United States 11/05/2022 06:52 PM Report Abusive Post Report Copyright Violation | If you read the article, that is the intent. I do believe I have read articles also stating that this is now the case. The following is from 2 days ago Vaccine Targeting Both Flu And Covid Starts Trials—As Scientists Test New Ways To Immunize People More Efficiently [link to www.msn.com (secure)] I honestly would stay as far away from the medical establishment as one can. Truthfully, I would rather die of natural causes than opt to enroll in some health service, surgery or treatment, where they expect me to take some mNRA concoction they are requiring people to accept if seeking medical treatment or preventative health care that might prolong ones life with said medical intervention. |
Anonymous Coward User ID: 79744929 Turkey 11/05/2022 06:53 PM Report Abusive Post Report Copyright Violation | It's a whole industry of biological weapons disguised aw "vaccines" and other medications. They've been building this industry for decades in secret. Quoting: Anonymous Coward 79324694 mRNA is just to soften-up the Target. mRNA is killing Immunesystem and Blood brain barrier |
Anonymous Coward User ID: 83962627 United States 11/05/2022 06:55 PM Report Abusive Post Report Copyright Violation | mRNA has potential for future treatments of things like cancer. Imagine creating mRNA that can cause cancer cells and only cancer cells to self destruct? That would be a lot safer than chemo Quoting: Anonymous Coward 84599932 The only reason to take a vaccine is if you will absolutely die without it. Like rabies or a snakebite which is rare. |
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Anonymous Coward User ID: 77691152 United States 11/05/2022 07:39 PM Report Abusive Post Report Copyright Violation | mRNA has potential for future treatments of things like cancer. Imagine creating mRNA that can cause cancer cells and only cancer cells to self destruct? That would be a lot safer than chemo Quoting: Anonymous Coward 84599932 The only reason to take a vaccine is if you will absolutely die without it. Like rabies or a snakebite which is rare. Sure, it’s gone so well at preventing Covid. |
Anonymous Coward User ID: 78770868 United States 11/05/2022 07:50 PM Report Abusive Post Report Copyright Violation | mRNA has potential for future treatments of things like cancer. Imagine creating mRNA that can cause cancer cells and only cancer cells to self destruct? That would be a lot safer than chemo Quoting: Anonymous Coward 84599932 The only reason to take a vaccine is if you will absolutely die without it. Like rabies or a snakebite which is rare. mRNA to cure cancer? LMAO fucking with genes is what causes cancer! There's a reason the immune system evolved over millions of years to nuke any foreign mRNA on sight. The mad scientists at pfizer/moderna found a way to bypass this natural evolutionary defense. |
Anonymous Coward User ID: 84540296 New Zealand 11/05/2022 08:07 PM Report Abusive Post Report Copyright Violation | mRNA has potential for future treatments of things like cancer. Imagine creating mRNA that can cause cancer cells and only cancer cells to self destruct? That would be a lot safer than chemo Quoting: Anonymous Coward 84599932 mRNA absolutely pissed (ALL OVER) the bed the first time. I mean it drenched every single pore on the bed with it's extreme ineffectiveness and obvious dangers. Why would we trust big pharma and their 'theoretical miracle technology' a second time? |
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Anonymous Coward User ID: 75107846 Canada 11/07/2022 09:38 AM Report Abusive Post Report Copyright Violation | mRNA has potential for future treatments of things like cancer. Imagine creating mRNA that can cause cancer cells and only cancer cells to self destruct? That would be a lot safer than chemo Quoting: Anonymous Coward 84599932 The problem with such a powerful technology is that people (scientists) will start to fuck around until they find out. In the course of that fucking around bad stuff can happen. Much like nuclear power I don't think humanity as a whole is not developed and wise enough to fuck around with such stuff. Exactly...."science" has out-driven it's headlights. Humanity's knowledge is exceeding it's wisdom! This will NOT end well. |
Anonymous Coward User ID: 84910260 United States 12/13/2022 09:29 AM Report Abusive Post Report Copyright Violation | Thread: BOMBSHELL: MAN in 2013 TRIAL WITH 200K PEOPLE TO TEST MRNA-BASED MEDICATION, less than 5 alive! Quoting: TerraFirma's Esoterrorist The takeway: Quoting: TerraFirma's Esoterrorist COVID illness (exposure to SARS-COV-2 bioweapon) is 99.99% Non Fatal. COVID mRNA "Investigative" injections are 99.99% Fatal ...within 9 years. www.bitchute.com/video/rZec9bjNmgFl/ :jay: |
sad pony
User ID: 80785597 United States 12/13/2022 02:48 PM Report Abusive Post Report Copyright Violation | mRNA has potential for future treatments of things like cancer. Imagine creating mRNA that can cause cancer cells and only cancer cells to self destruct? That would be a lot safer than chemo Quoting: Anonymous Coward 84599932 I’m talking about future potential mRNA technology, but current ‘vaccines’ Oh,so you actually believe that they want to cure cancer, the huge money maker for them? Yeah, right sure they do. There's already been several safe ways to cure cancer for years now. Those methods have been completely suppressed, like many other things that would be a benefit to us. Get real, any mRNA technology is going to be used for bad purposes where it concerns us anyway. You are correct 100% |