What’s your monkeypox plan? | |
docsquat
User ID: 82561383 United States 05/22/2022 08:32 AM Report Abusive Post Report Copyright Violation | |
SafeandSound
(OP) User ID: 81103575 United States 05/22/2022 08:35 AM Report Abusive Post Report Copyright Violation | |
Marvelous Man
User ID: 58686169 United States 05/22/2022 08:36 AM Report Abusive Post Report Copyright Violation | [link to rwmalonemd.substack.com (secure)] Monkeypox is a double stranded DNA virus, which means that due to the double stranded nature of DNA each of the two strands act as a “check” on the other during replication. As a consequence of this “error checking”, this and other DNA viruses mutate much more slowly than RNA viruses do. Over time, DNA virus genomes are relatively stable. This means that, unlike SARS-CoV-2 (COVID) or influenza, Monkeypox is unlikely to rapidly evolve to escape either naturally acquired or vaccine induced immunity. For the purposes of making a vaccine, this makes it a much easier target that say, a rapidly evolving RNA Coronavirus such as SARS-CoV-2, the virus which causes COVID-19. Furthermore, from an immunological point of view, the various Orthopox viruses often are cross-protective. In other words, if you have been vaccinated with a smallpox vaccine, or previously infected by Cowpox, Camelpox, or Monkeypox, you are highly likely to be quite resistant to disease caused by the Monkeypox virus which is now being (quite rarely) reported in non-African countries. Current data indicate that Monkeypox is not very infectious in humans - it has a low Ro (perhaps below 1), which is the term used to describe how efficiency an infectious disease can spread from human to human. Again, this is super good news for containment. An Ro of <1 generally means that (even in the absence of social distancing of other containment measures), for every person already infected, on average less than one other person will become infected. For comparison purposes, the Omicron variants of SARS-CoV-2 have an Ro in the range of 7 to 10. A virus with an Ro of less than one can be easily contained with the standard public health methods discussed above. A virus with an Ro of 7-10 essentially cannot be contained and will rapidly spread throughout the world, as we have seen with the Omicron variants. In the case of a virus with an Ro around 1 or less, traditional infectious disease containment methods such as contact tracing, identification and isolation of infected individuals can be all that is needed to control the virus. Now the fact that Monkeypox is being spread from human to human (rather than only arising from contact between a person and an infected animal) is not such good news, but since this transmission appears to be from very close contact, this means that it can be easily contained without resorting to a general population vaccination campaign. In this type of setting, if there is a significant outbreak, vaccination is often restricted to just the health care and/or first responder personnel most likely to be in contact with an infected person. Using a vaccine to help that containment via either “ring” vaccination or wide-spread vaccination strategies is generally unnecessary, and may even be counterproductive, depending on the safety of the vaccine - keeping in mind that no drug or vaccine is perfectly safe. There are two ways to be fooled. One is to believe what isn’t true; the other is to refuse to believe what is true. |
Big Daddy D
Chaotic Constitutionalist User ID: 82123025 United States 05/22/2022 08:50 AM Report Abusive Post Report Copyright Violation | |
The Juan Mower
User ID: 49614807 United States 05/22/2022 08:53 AM Report Abusive Post Report Copyright Violation | |
Marvelous Man
User ID: 58686169 United States 05/22/2022 08:54 AM Report Abusive Post Report Copyright Violation | |
Anonymous Coward User ID: 82235185 Moldova 05/22/2022 08:54 AM Report Abusive Post Report Copyright Violation | |
Anonymous Coward User ID: 82734976 United States 05/22/2022 08:55 AM Report Abusive Post Report Copyright Violation | |
Anonymous Coward User ID: 22271610 United States 05/22/2022 08:56 AM Report Abusive Post Report Copyright Violation | |
Sharon Cherries
User ID: 81142270 United States 05/22/2022 08:58 AM Report Abusive Post Report Copyright Violation | |
ShortStop
User ID: 82820048 United States 05/22/2022 09:05 AM Report Abusive Post Report Copyright Violation | |
ScrumpTheTexan
Forum Administrator 05/22/2022 09:17 AM Report Abusive Post Report Copyright Violation | To ignore it completely. I am a Christian. Christian does not equal doormat or pushover "I Have Sworn upon the Altar of God... Eternal Hostility against every form of Tyranny over the mind of man." -Thomas Jefferson, Sep. 23, 1800 The Election of Donald John Trump: [link to www.godlikeproductions.com] For previous Newsletters, click 'Scrump's News Letters' @ [link to www.godlikeproductions.com] |
Anonymous Coward User ID: 82573275 United States 05/22/2022 09:20 AM Report Abusive Post Report Copyright Violation | |
Mdc61170
User ID: 80415401 United States 05/22/2022 09:20 AM Report Abusive Post Report Copyright Violation | |
cancer sucks
User ID: 82115820 United States 05/22/2022 09:21 AM Report Abusive Post Report Copyright Violation | |
FBHO
User ID: 76785567 United States 05/22/2022 09:21 AM Report Abusive Post Report Copyright Violation | Marxism is the true enemy of our civilization. What is Cultural Marxism: [link to www.bitchute.com (secure)] |
Anonymous Coward User ID: 82825741 United States 05/22/2022 09:22 AM Report Abusive Post Report Copyright Violation | |
Rebeluciono
User ID: 78342790 United States 05/22/2022 09:23 AM Report Abusive Post Report Copyright Violation | |
Anonymous Coward User ID: 74979867 United Kingdom 05/22/2022 09:25 AM Report Abusive Post Report Copyright Violation | |
last one
I just don't give a fuck User ID: 60052792 United States 05/22/2022 09:25 AM Report Abusive Post Report Copyright Violation | |
Anonymous Coward User ID: 82573275 United States 05/22/2022 09:26 AM Report Abusive Post Report Copyright Violation | |
Anonymous Coward User ID: 80104801 Canada 05/22/2022 09:26 AM Report Abusive Post Report Copyright Violation | |
AcCthulhu
User ID: 83362406 United States 05/22/2022 09:27 AM Report Abusive Post Report Copyright Violation | |
Black Unit
User ID: 13767076 United States 05/22/2022 09:28 AM Report Abusive Post Report Copyright Violation | [link to rwmalonemd.substack.com (secure)] Quoting: Marvelous Man Monkeypox is a double stranded DNA virus, which means that due to the double stranded nature of DNA each of the two strands act as a “check” on the other during replication. As a consequence of this “error checking”, this and other DNA viruses mutate much more slowly than RNA viruses do. Over time, DNA virus genomes are relatively stable. This means that, unlike SARS-CoV-2 (COVID) or influenza, Monkeypox is unlikely to rapidly evolve to escape either naturally acquired or vaccine induced immunity. For the purposes of making a vaccine, this makes it a much easier target that say, a rapidly evolving RNA Coronavirus such as SARS-CoV-2, the virus which causes COVID-19. Furthermore, from an immunological point of view, the various Orthopox viruses often are cross-protective. In other words, if you have been vaccinated with a smallpox vaccine, or previously infected by Cowpox, Camelpox, or Monkeypox, you are highly likely to be quite resistant to disease caused by the Monkeypox virus which is now being (quite rarely) reported in non-African countries. Current data indicate that Monkeypox is not very infectious in humans - it has a low Ro (perhaps below 1), which is the term used to describe how efficiency an infectious disease can spread from human to human. Again, this is super good news for containment. An Ro of <1 generally means that (even in the absence of social distancing of other containment measures), for every person already infected, on average less than one other person will become infected. For comparison purposes, the Omicron variants of SARS-CoV-2 have an Ro in the range of 7 to 10. A virus with an Ro of less than one can be easily contained with the standard public health methods discussed above. A virus with an Ro of 7-10 essentially cannot be contained and will rapidly spread throughout the world, as we have seen with the Omicron variants. In the case of a virus with an Ro around 1 or less, traditional infectious disease containment methods such as contact tracing, identification and isolation of infected individuals can be all that is needed to control the virus. Now the fact that Monkeypox is being spread from human to human (rather than only arising from contact between a person and an infected animal) is not such good news, but since this transmission appears to be from very close contact, this means that it can be easily contained without resorting to a general population vaccination campaign. In this type of setting, if there is a significant outbreak, vaccination is often restricted to just the health care and/or first responder personnel most likely to be in contact with an infected person. Using a vaccine to help that containment via either “ring” vaccination or wide-spread vaccination strategies is generally unnecessary, and may even be counterproductive, depending on the safety of the vaccine - keeping in mind that no drug or vaccine is perfectly safe. Terrific article by Dr. Malone |
Tiaka9
User ID: 83278480 United Kingdom 05/22/2022 09:28 AM Report Abusive Post Report Copyright Violation | Bullous pemphigoid (blisters) after second dose of mRNA- (Pfizer-BioNTech) Covid-19 vaccine: A case report [link to www.ncbi.nlm.nih.gov (secure)] |
Emergency Patriot Hologram
User ID: 80986529 Spain 05/22/2022 09:28 AM Report Abusive Post Report Copyright Violation | I'm going to put on fake spots om my arms, hands and face and scare everyone at the supermarket. Afterlife menu Play again (y/n) y Use same avatar (y/n) y Replay previous game (y/n) y Retain avatar memory (y/n) y WARNING: current avatar memory will be gradually inserted between the Earth ages of six and twelve. Are you sure you want to do this (y/n) y Press Enter to start or Ctrl+X to abort |
Anonymous Coward User ID: 83362413 Jamaica 05/22/2022 09:29 AM Report Abusive Post Report Copyright Violation | |
Anonymous Coward User ID: 67954698 United States 05/22/2022 09:30 AM Report Abusive Post Report Copyright Violation | |
Anonymous Coward User ID: 78372339 United States 05/22/2022 09:32 AM Report Abusive Post Report Copyright Violation | |
Anonymous Coward User ID: 81674768 Canada 05/22/2022 09:32 AM Report Abusive Post Report Copyright Violation | |