The author explains the footnotes better than me.

Basically there would be a report somewhere of some effect. But it could not be reproduced and the report was not verifiable.

Such as a report of Liver toxicity. But the patient might have already had the condition as a heavy drinker.

Or a report of extreme low blood pressure in someone that was LOADED with the Onchocercius worm (river blindness worm).
[link to en.wikipedia.org (secure)]


Or effects on pregnant mice.

Just adding my 2 cents. I am not a doctor, so again I would just listen to the guy with the PhD that is reviewing the paper of the guy with 3 PhDs.

But my useless comments, since you asked would be the following:

If I was a pregnant woman, I would not wish to tempt fate, regardless of what the report says. I would not do prophylaxis and would only use it in an emergency, with a doctor's blessing.

If I knew I had a defective blood brain barrier, such as might occur with a brain infection, I would be working with a doctor to get the best advice.

Or if you overdose the stuff in the extreme, like swallow a whole bottle of the pills.

He stresses that there is an excellent "therapeutic margin" with Ivermectin, ie the dose to treat is quite far from the dose that can cause harm.

If you are on Warfarin, or really any drugs, I would research possible interactions with Ivermectin.

But in summary, the drug is exceedingly safe.

If you are full of worms, the worms are going to die. The worms will lose the slime layer that masks them from your immune system. Then the immune system will kick in and do battle with the worm debris. This can cause some symptoms.

Again, I am not a doctor. I would suggest listening to the doctor in the video with a degree on the subject matter, even though it takes 37 minutes.