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OMG - Article About Moderna's mRNA Technology From 2017

 
Anonymous Coward
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OMG - Article About Moderna's mRNA Technology From 2017
His presentation instead focused on four vaccines that the company is moving through the first phase of clinical trials: two target strains of influenza, a third is for Zika virus, and the fourth remains a secret.

[link to www.statnews.com (secure)]

This is a long article but well worth the read!!!!
Zovalex

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04/14/2021 06:15 PM
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Re: OMG - Article About Moderna's mRNA Technology From 2017
Outstanding find!

It details the many problems Moderna has had in developing an mRNA vaccine.

I saved this article as a PDF because it will likely be deleted off the internet.

.
“Mental slavery is the worst form of slavery.
It gives you the illusion of freedom,
makes you trust, love, and defend your oppressor,
while making an enemy of those
who are trying to free you or open your eyes.”
-Fiyah

“None are more hopelessly enslaved than those who falsely believe they are free.”
-Johann Wolfgang von Goethe

“You have been programmed to resist the very person that is here to set you free, from the prison of your Mind... You are not free... everything you are has been manufactured by Minds that have not your best interest. You are imprisoned by beliefs and not reality. Religions are mental programs to imprison your Mind.”

-SOL
Garbo

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Re: OMG - Article About Moderna's mRNA Technology From 2017
bump
TheEmptyChild

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04/14/2021 06:42 PM
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Re: OMG - Article About Moderna's mRNA Technology From 2017
Isn't it true that Moderna has never actually successfully released a "vaccine?"
Now their first one is being injected into the the general population. Well...that will definitely end well.
Anonymous Coward
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04/14/2021 06:43 PM
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Re: OMG - Article About Moderna's mRNA Technology From 2017
bump
chrion777

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04/14/2021 06:58 PM

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Re: OMG - Article About Moderna's mRNA Technology From 2017
His presentation instead focused on four vaccines that the company is moving through the first phase of clinical trials: two target strains of influenza, a third is for Zika virus, and the fourth remains a secret.

[link to www.statnews.com (secure)]

This is a long article but well worth the read!!!!
 Quoting: Anonymous Coward 78343423


One interesting thing is that they note that V1GL may allow them to deliver vaccines safer.

"V1GL, a next-generation lipid nanoparticle technology"

So conceptually, the new mRNA are safer then all the ones that previously failed in animal trials.

I'm not 100% sure but I think it's something like this. Prior to the lipid technology they would have to either give a small dose and then the mRNA would quickly decay and not generate an immune response or give a VERY high dose and it would have severe complications.

The the lipid technology is basically a type of time release supporting the self-amplification of mRNA up until the time that the substrate is used up.

Therefore it allows to give that moderate dose. If you remember in the human trials the maximum dose had severe side effects and they had to back off on the top dosage level and settle on the medium dose which has 'strong side effects' but not as severe. In other words people get hit hard with fatigue, headache but generally not more then that (for most people). To date, it is true that very severe side effects are very rare, and even the cases of monitoring and hospitalization most of them resolve without incident.

The problem is we DO NOT KNOW the intermeate and long term effects:


1. Antibody Dependent Enhancement (ADE)

2. Potential impact to fertility

3. Potential cause of auto-immune illness

4. Effectiveness against other strains

5. Immune thrombocytopenia

6. Prions?? Not sure if this would generate enough prions or if they would cross the blood brain barrier. It should not generate more prions then just first few days after inoculation so I would kind of expect we would see prion disease rather quickly if it was going to occur. Not sure if there would be a commutative effect with boosters, or if misfolden proteins would take time to manifest or some how complicate themselves over time without new prions being created.

I'm not too worried about prion disease yet but I'm watching all of it to see how it plays out.
Alpacalips

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04/14/2021 07:00 PM

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Re: OMG - Article About Moderna's mRNA Technology From 2017
bump
Anonymous Coward
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04/14/2021 07:01 PM
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Re: OMG - Article About Moderna's mRNA Technology From 2017
A secret? Yea right
Anonymous Coward
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Re: OMG - Article About Moderna's mRNA Technology From 2017
MARK OF THE BEAST
Herr Decider

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04/14/2021 07:03 PM
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Re: OMG - Article About Moderna's mRNA Technology From 2017
His presentation instead focused on four vaccines that the company is moving through the first phase of clinical trials: two target strains of influenza, a third is for Zika virus, and the fourth remains a secret.

[link to www.statnews.com (secure)]

This is a long article but well worth the read!!!!
 Quoting: Anonymous Coward 78343423


One interesting thing is that they note that V1GL may allow them to deliver vaccines safer.

"V1GL, a next-generation lipid nanoparticle technology"

So conceptually, the new mRNA are safer then all the ones that previously failed in animal trials.

I'm not 100% sure but I think it's something like this. Prior to the lipid technology they would have to either give a small dose and then the mRNA would quickly decay and not generate an immune response or give a VERY high dose and it would have severe complications.

The the lipid technology is basically a type of time release supporting the self-amplification of mRNA up until the time that the substrate is used up.

Therefore it allows to give that moderate dose. If you remember in the human trials the maximum dose had severe side effects and they had to back off on the top dosage level and settle on the medium dose which has 'strong side effects' but not as severe. In other words people get hit hard with fatigue, headache but generally not more then that (for most people). To date, it is true that very severe side effects are very rare, and even the cases of monitoring and hospitalization most of them resolve without incident.

The problem is we DO NOT KNOW the intermeate and long term effects:


1. Antibody Dependent Enhancement (ADE)

2. Potential impact to fertility

3. Potential cause of auto-immune illness

4. Effectiveness against other strains

5. Immune thrombocytopenia

6. Prions?? Not sure if this would generate enough prions or if they would cross the blood brain barrier. It should not generate more prions then just first few days after inoculation so I would kind of expect we would see prion disease rather quickly if it was going to occur. Not sure if there would be a commutative effect with boosters, or if misfolden proteins would take time to manifest or some how complicate themselves over time without new prions being created.

I'm not too worried about prion disease yet but I'm watching all of it to see how it plays out.
 Quoting: chrion777


All that needs to happen is one spike protein crosses the blood brain barrier, and the prion like domain is triggered to generate ONE infectious misfolded prion.

That misfolded prion is infectious in that it will vibrate and misfold any endogenous prion it comes upon, and there are plenty of them in the brain.

it is a domino effect b/c as long as a misfolded prion remains in existence, it can convert normal prions.

Which is why they are considered "infectious". It's a domino effect.
Augmented by Grace
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Re: OMG - Article About Moderna's mRNA Technology From 2017
Company was "in need of a hail Mary" and whaddya know?

If you are participating in this society at any level beyond your own survival, you are a fucking moron & deserve exactly what your corporate masters have planned for you.
Crypto-Tard

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Re: OMG - Article About Moderna's mRNA Technology From 2017
Isn't it true that Moderna has never actually successfully released a "vaccine?"
Now their first one is being injected into the the general population. Well...that will definitely end well.
 Quoting: TheEmptyChild


It's an experimental medical protocol, not a vaccine.

Let's see how things end up in 2023, when they are going to try to get approved as a vaccine.
When you are afraid of losing your life, you have already lost your life.

Don't be afraid.
TheEmptyChild

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04/14/2021 07:18 PM
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Re: OMG - Article About Moderna's mRNA Technology From 2017
Isn't it true that Moderna has never actually successfully released a "vaccine?"
Now their first one is being injected into the the general population. Well...that will definitely end well.
 Quoting: TheEmptyChild


It's an experimental medical protocol, not a vaccine.

Let's see how things end up in 2023, when they are going to try to get approved as a vaccine.
 Quoting: Crypto-Tard


I will continue to maintain that I have been self appointed to the control group.
stonefly

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04/14/2021 07:20 PM
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Re: OMG - Article About Moderna's mRNA Technology From 2017
Isn't it true that Moderna has never actually successfully released a "vaccine?"
Now their first one is being injected into the the general population. Well...that will definitely end well.
 Quoting: TheEmptyChild




"Never"? could be I don't know the companies history but I do know that no company has produced a "Vaccine" for the bioweapon.

they can characterize it as an "MRNA" Vaccine like that's ok somehow but we can see they are conflating it with an actual Vaccine.

In my experience when someone is going to a good deal of trouble to convince you a thing is safe....it isn't.
stonefly
TheEmptyChild

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04/14/2021 07:25 PM
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Re: OMG - Article About Moderna's mRNA Technology From 2017
Yes...I know. Technically none of this poison is considered a vaccine. When they extracted pus out of someone's festering sore, who had small pox, and pushed it into a cut on your arm...THAT was a vaccine. The term is used loosely. It's all bullshit and it's going to kill people.
Anonymous Coward
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04/14/2021 07:26 PM
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Re: OMG - Article About Moderna's mRNA Technology From 2017
His presentation instead focused on four vaccines that the company is moving through the first phase of clinical trials: two target strains of influenza, a third is for Zika virus, and the fourth remains a secret.

[link to www.statnews.com (secure)]

This is a long article but well worth the read!!!!
 Quoting: Anonymous Coward 78343423


“mRNA is like software: You can just turn the crank and get a lot of products going into development.”
Anonymous Coward
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04/14/2021 07:33 PM
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Re: OMG - Article About Moderna's mRNA Technology From 2017
His presentation instead focused on four vaccines that the company is moving through the first phase of clinical trials: two target strains of influenza, a third is for Zika virus, and the fourth remains a secret.

[link to www.statnews.com (secure)]

This is a long article but well worth the read!!!!
 Quoting: Anonymous Coward 78343423


Secret because its Sars-Cov 2
Anonymous Coward
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04/14/2021 07:38 PM
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Re: OMG - Article About Moderna's mRNA Technology From 2017
Yes...I know. Technically none of this poison is considered a vaccine. When they extracted pus out of someone's festering sore, who had small pox, and pushed it into a cut on your arm...THAT was a vaccine. The term is used loosely. It's all bullshit and it's going to kill people.
 Quoting: TheEmptyChild


All those Zombie movies....All those Zombie movies....as it turned out, they were a future survival guide, lol.
CigarTigher

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04/14/2021 07:47 PM

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bump
Anonymous Coward
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04/14/2021 08:01 PM
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Re: OMG - Article About Moderna's mRNA Technology From 2017
good read, one thing came to mind...Frankenstein's monster, to small of a dose it doesn't work, to much of a dose it becomes toxic to the subject. Another word come to mind reading it to snake oil salesman. Playing russian roulette with people isn't medicine.
c major
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04/14/2021 08:04 PM
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Re: OMG - Article About Moderna's mRNA Technology From 2017
Isn't it true that Moderna has never actually successfully released a "vaccine?"
Now their first one is being injected into the the general population. Well...that will definitely end well.
 Quoting: TheEmptyChild


mo=moses d' erna ( by works)
Anonymous Coward
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04/14/2021 08:06 PM
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Re: OMG - Article About Moderna's mRNA Technology From 2017
Founded in 2012, Moderna reached unicorn status — a $1 billion valuation — in just two years, faster than Uber, Dropbox, and Lyft, according to CB Insights. The company’s premise: Using custom-built strands of messenger RNA, known as mRNA, it aims to turn the body’s cells into ad hoc drug factories, compelling them to produce the proteins needed to treat a wide variety of diseases
Anonymous Coward
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04/14/2021 08:08 PM
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Re: OMG - Article About Moderna's mRNA Technology From 2017
You so called 'awakened' are everything but awake. No, YOU IN F A C T are the sheep. You really think there is something to discuss ?!? You really think there is some greater T R U T H which needs to be agreed upon ?!?

I SAY ' F U C K Y O U ' - YOU with your nobody - YOU with your wisdom - YOU with your lucifer - YOU with your god - YOU with your jesus - YOU with your buddha - YOU with your satan - YOU with your politicians - YOU with your celebrities - YOU with your alternative viewpoints - fuck YOU!

FUCK YOU - YOU APOLOGISTS !
 Quoting: Just let me tell you 79882337


blahblah5
chrion777

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04/14/2021 08:23 PM

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Re: OMG - Article About Moderna's mRNA Technology From 2017
His presentation instead focused on four vaccines that the company is moving through the first phase of clinical trials: two target strains of influenza, a third is for Zika virus, and the fourth remains a secret.

[link to www.statnews.com (secure)]

This is a long article but well worth the read!!!!
 Quoting: Anonymous Coward 78343423


One interesting thing is that they note that V1GL may allow them to deliver vaccines safer.

"V1GL, a next-generation lipid nanoparticle technology"

So conceptually, the new mRNA are safer then all the ones that previously failed in animal trials.

I'm not 100% sure but I think it's something like this. Prior to the lipid technology they would have to either give a small dose and then the mRNA would quickly decay and not generate an immune response or give a VERY high dose and it would have severe complications.

The the lipid technology is basically a type of time release supporting the self-amplification of mRNA up until the time that the substrate is used up.

Therefore it allows to give that moderate dose. If you remember in the human trials the maximum dose had severe side effects and they had to back off on the top dosage level and settle on the medium dose which has 'strong side effects' but not as severe. In other words people get hit hard with fatigue, headache but generally not more then that (for most people). To date, it is true that very severe side effects are very rare, and even the cases of monitoring and hospitalization most of them resolve without incident.

The problem is we DO NOT KNOW the intermeate and long term effects:


1. Antibody Dependent Enhancement (ADE)

2. Potential impact to fertility

3. Potential cause of auto-immune illness

4. Effectiveness against other strains

5. Immune thrombocytopenia

6. Prions?? Not sure if this would generate enough prions or if they would cross the blood brain barrier. It should not generate more prions then just first few days after inoculation so I would kind of expect we would see prion disease rather quickly if it was going to occur. Not sure if there would be a commutative effect with boosters, or if misfolden proteins would take time to manifest or some how complicate themselves over time without new prions being created.

I'm not too worried about prion disease yet but I'm watching all of it to see how it plays out.
 Quoting: chrion777


All that needs to happen is one spike protein crosses the blood brain barrier, and the prion like domain is triggered to generate ONE infectious misfolded prion.

That misfolded prion is infectious in that it will vibrate and misfold any endogenous prion it comes upon, and there are plenty of them in the brain.

it is a domino effect b/c as long as a misfolded prion remains in existence, it can convert normal prions.

Which is why they are considered "infectious". It's a domino effect.
 Quoting: Herr Decider


*$*# you are right. Why would they want to give everyone a degenerative brain disease. Talk about a sick way to take out the population.

Now I'm still not sure how likely this will be in real life; it looks like it is a plausable risk and we should be sure before injecting millions of people with mRNA.

Do you think the Novavax protein sub-unit vaccine would be less likely to generate misfolded proteins since it is a smaller fragment

From Wikipedia:
[link to en.wikipedia.org (secure)]

transmissible.[98] This has given rise to the 'prion paradigm', where otherwise harmless proteins can be converted to a pathogenic form by a small number of misfolded, nucleating proteins.[99]
Anonymous Coward
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Re: OMG - Article About Moderna's mRNA Technology From 2017
Terrebonne

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Re: OMG - Article About Moderna's mRNA Technology From 2017
All those Zombie movies....All those Zombie movies....as it turned out, they were a future survival guide, lol.

Zombie2
 Quoting: Anonymous Coward 80243663


indeed

.
INFJ; We are the protectors.
Save America From Politicians

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Re: OMG - Article About Moderna's mRNA Technology From 2017
That's a fucking great article and everyone needs to read it, starts off slow but solidifies my stance on how fucked up the whole situation really is.
Anonymous Coward
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04/14/2021 09:14 PM
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Re: OMG - Article About Moderna's mRNA Technology From 2017
Isn't it true that Moderna has never actually successfully released a "vaccine?"
Now their first one is being injected into the the general population. Well...that will definitely end well.
 Quoting: TheEmptyChild


.



so you still do not realize emergency order is gree nlight for experimental human trials....






.
Anonymous Coward
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04/14/2021 09:17 PM
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Re: OMG - Article About Moderna's mRNA Technology From 2017
bump
Anonymous Coward
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Re: OMG - Article About Moderna's mRNA Technology From 2017
Isn't it true that Moderna has never actually successfully released a "vaccine?"
Now their first one is being injected into the the general population. Well...that will definitely end well.
 Quoting: TheEmptyChild




This was my understanding as well.

Seems it was manufactured in India, distributed by Moderna.
sos

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Re: OMG - Article About Moderna's mRNA Technology From 2017
Latest video from Kevin McCairn PhD, systems neuroscientist, on his mccairndojo.com site. He’s still banned from uploading videos on YouTube.

“Updated Neuroscience of the COVIDzombie Swarm”

He goes over new papers.

A snippet of a comment on one of the papers ...

“The binding site, the receptor binding motif of SARS-CoV-2, will trigger the amyloid cascade for Alzheimer’s-like degeneration and now we are going to find out that the N-terminal region can trigger the alpha-synuclein cascade. Both the virus and the vaccine will do it.

My advice, if you can, hunker down for another 6 months. Let’s get more data. The vaccines started, what, 6 months ago. Now let’s give it 6 more months and see what we see. Then you are going to have to make a decision.

We may get into a Marek’s situation and you’ll be at the end of a corporate needle for the rest of your life and so will your kids.”
 Quoting: sos





GLP