Confirmed! Spike proteins can signal cells! Causing pathogenesis! | |
Union Jackboot
User ID: 76689556 United States 03/20/2021 07:39 AM Report Abusive Post Report Copyright Violation | |
Man Of Kent
User ID: 79286275 United Kingdom 03/20/2021 07:54 AM Report Abusive Post Report Copyright Violation | |
Patriotic Black dude
User ID: 79904131 United States 03/20/2021 07:56 AM Report Abusive Post Report Copyright Violation | |
evangeline claire
User ID: 77590476 United States 03/20/2021 08:00 AM Report Abusive Post Report Copyright Violation | What a load of horseshit. Quoting: Man Of Kent Covid hasn't been isolated, it doesn't exist. This is the biggest hoax in the history of the world But the creation of a spike protein from the vaxx does occur. Isaiah 5:20 Woe to those who call evil good, and good evil; Who put darkness for light, and light for darkness; Who put bitter for sweet, and sweet for bitter! |
docsquat
User ID: 80150206 United States 03/20/2021 08:01 AM Report Abusive Post Report Copyright Violation | |
Anonymous Coward User ID: 80144211 United States 03/20/2021 08:02 AM Report Abusive Post Report Copyright Violation | |
Artificial Person
User ID: 78544494 Canada 03/20/2021 08:07 AM Report Abusive Post Report Copyright Violation | |
tkwasny
User ID: 77839169 United States 03/20/2021 08:14 AM Report Abusive Post Report Copyright Violation | People can't perform application of the 7th grade fundamentals of geometry. If the thread count (mesh dimensions) of any N95 or N99 mask is hundreds of times WIDER apart than the size of a pathogen, it's a hot dog down the hallway. |
GeorgeSumner'sAcorn
User ID: 77479307 United States 03/20/2021 08:19 AM Report Abusive Post Report Copyright Violation | GLP already knew this, but for people like my dad who has done no research outside of CNN and called me stupid for not wanting the shot, and who said that he hopes "they"hold me down to get it....... In 1839 20-year-old George Sumner sailed from the US to Russia, as supercargo on freighter.He carried with him an acorn,taken from the grave of Washington.He talked his way into the presence of Czar Nicholas I and presented the Acorn as a gift from America. The Czar was charmed. The story.... |
nutmeg
User ID: 76388104 United States 03/20/2021 08:19 AM Report Abusive Post Report Copyright Violation | |
Anonymous Coward User ID: 80144211 United States 03/20/2021 08:22 AM Report Abusive Post Report Copyright Violation | |
Anonymous Coward User ID: 80144211 United States 03/20/2021 08:23 AM Report Abusive Post Report Copyright Violation | |
KingMarduk
(OP) User ID: 80146885 Malaysia 03/20/2021 08:25 AM Report Abusive Post Report Copyright Violation | One more VERY IMPORTANT! They have 2 DIFFERENT vaccines of the same brand, one for the elites, one for YOU. Elites get the safe BNT162b1 YOU get the BNT162b2 that is much riskier! This vaccine seems engineered to terminate certain weak/common people. 5. RBD Only-Containing SARS-CoV-2 Spike Protein Does Not Elicit Cell Signaling in Human Cells In contrast to the full-length spike protein [26,29] or the full-length SARS-CoV-2 spike protein S1 subunit [21], we found that the RBD only-containing protein (Figure 1) did not promote cell signaling. Our Western blotting results monitoring the MEK activation showed that the mean ± SEM phosphorylated MEK to MEK protein ratio values were 0.05 ± 0.003 (untreated), 1.9 ± 0.07 (treated with the full-length S1 protein), and 0.05 ± 0.003 (treated with the RBD only-containing protein) for human pulmonary artery SMCs; and 0.09 ± 0.006 (untreated), 0.90 ± 0.06 (treated with the full-length S1 protein), and 0.10 ± 0.003 (treated with the RBD only-containing protein) for human pulmonary artery endothelial cells [21]. The different effects of the full-length S1 and RBD only-containing proteins may be important considering that BNT162b2 and many other COVID-19 vaccines express the full-length spike protein, while the BNT162b1 vaccine encodes only the RBD region [9,10,11,12,13,14,15,16,17,18,19,20]. There are some other RBD-based COVID-19 vaccines being developed as well [43]. It is possible that the RBD-based vaccines are less immunogenic, but may not affect the host cells. Thus, they may be less risky considering potential long-term adverse effects. However, in the in vivo study of the SARS-CoV-1 spike protein described above [28], a deletion mutant that only contained the RBD also worsened the acid-induced lung failure, like the full-length spike protein. Thus, further work is needed to understand effects of the full-length spike protein and the RBD-only containing protein in various biological processes. |
Conservative Moppie
User ID: 39634629 United States 03/20/2021 08:39 AM Report Abusive Post Report Copyright Violation | GLP already knew this, but for people like my dad who has done no research outside of CNN and called me stupid for not wanting the shot, and who said that he hopes "they"hold me down to get it....... Quoting: GeorgeSumner'sAcorn Tell your father it is actually possible to die of stupidity. We have a relative who is an uber liberal and has been in terrible shape for a couple of weeks now after her shot. She is not expected to make it. |
LTHN.
User ID: 80126918 Canada 03/20/2021 08:42 AM Report Abusive Post Report Copyright Violation | What a load of horseshit. Quoting: Man Of Kent Covid hasn't been isolated, it doesn't exist. This is the biggest hoax in the history of the world No, the biggest hoax is that a mask can stop a virus Lol. "A wise man listens to the message and uses his logic and discernment to process it, a fool negates the message by prejudging the messenger." "He whose centre is everywhere and whose circumference is nowhere." |
LTHN.
User ID: 80126918 Canada 03/20/2021 08:43 AM Report Abusive Post Report Copyright Violation | there is no covid. all coronovirus have spikes... lets stop garbage today ok. Hear hear! Bravo! "A wise man listens to the message and uses his logic and discernment to process it, a fool negates the message by prejudging the messenger." "He whose centre is everywhere and whose circumference is nowhere." |
KingMarduk
(OP) User ID: 80146885 Malaysia 03/20/2021 08:45 AM Report Abusive Post Report Copyright Violation | You guys are spamming and not focusing on the points I highlighted. These vaccines seem to have 2 sets, one for the elite, one for the rest of us. One of them can cause issues like clots, strokes, cardiac arrest. Why is there 2 different vaccines if not for the safer one being used by the elite to convince you all to take that shit and you be given the dangerous one. |
TemperanceLaw
User ID: 72372974 United States 03/20/2021 08:55 AM Report Abusive Post Report Copyright Violation | |
LTHN.
User ID: 80126918 Canada 03/20/2021 08:57 AM Report Abusive Post Report Copyright Violation | You guys are spamming and not focusing on the points I highlighted. Quoting: KingMarduk These vaccines seem to have 2 sets, one for the elite, one for the rest of us. One of them can cause issues like clots, strokes, cardiac arrest. Why is there 2 different vaccines if not for the safer one being used by the elite to convince you all to take that shit and you be given the dangerous one. I read there are 2 different vaccines, I only read your thought that one was for the elite, and one for the common folks. It would make sense, no proof thought that is the case. "A wise man listens to the message and uses his logic and discernment to process it, a fool negates the message by prejudging the messenger." "He whose centre is everywhere and whose circumference is nowhere." |
Agent 99
User ID: 77082640 United States 03/20/2021 08:58 AM Report Abusive Post Report Copyright Violation | |
Agent 99
User ID: 77082640 United States 03/20/2021 08:59 AM Report Abusive Post Report Copyright Violation | You guys are spamming and not focusing on the points I highlighted. Quoting: KingMarduk These vaccines seem to have 2 sets, one for the elite, one for the rest of us. One of them can cause issues like clots, strokes, cardiac arrest. Why is there 2 different vaccines if not for the safer one being used by the elite to convince you all to take that shit and you be given the dangerous one. Genocide. Clearly. Necessary. |
Agent Smith 2014
User ID: 78229788 United Kingdom 03/20/2021 09:00 AM Report Abusive Post Report Copyright Violation | [link to www.mdpi.com (secure)] Quoting: KingMarduk 6. Discussion It is generally thought that the sole function of viral membrane fusion proteins is to allow the viruses to bind to the host cells for the purpose of viral entry into the cells, so that the genetic materials can be released and the viral replication and amplification can take place. However, recent observations suggest that the SARS-CoV-2 spike protein can by itself trigger cell signaling that can lead to various biological processes. It is reasonable to assume that such events, in some cases, result in the pathogenesis of certain diseases. Our laboratory only tested the effects of the SARS-CoV-2 spike protein in lung vascular cells and those implicated in the development of PAH. However, this protein may also affect the cells of systemic and coronary vasculatures, eliciting other cardiovascular diseases such as coronary artery disease, systemic hypertension, and stroke. In addition to cardiovascular cells, other cells that express ACE2 have the potential to be affected by the SARS-CoV-2 spike protein, which may cause adverse pathological events. Thus, it is important to consider the possibility that the SARS-CoV-2 spike protein produced by the new COVID-19 vaccines triggers cell signaling events that promote PAH, other cardiovascular complications, and/or complications in other tissues/organs in certain individuals (Figure 3). We will need to monitor carefully the long-term consequences of COVID-19 vaccines that introduce the spike protein into the human body. Furthermore, while human data on the possible long-term consequences of spike protein-based COVID-19 vaccines will not be available soon, it is imperative that appropriate experimental animal models are employed as soon as possible to ensure that the SARS-CoV-2 spike protein does not elicit any signs of the pathogenesis of PAH or any other chronic pathological conditions. The governmnet officials and elites dont want to know about this, they only want to skip to the end step which is mass selling and distribution of the vaccines around the world so they can make MONEY!!! The adverse affects do not matter to their short term narrow minded selfish goals. This is why they cut all the red tape and legislation surrounding the vaccines and why the big pharma compaines that make them are immune to lawsuits. Life is a dream and we are the imagination of ourselves. |
TemperanceLaw
User ID: 72372974 United States 03/20/2021 09:01 AM Report Abusive Post Report Copyright Violation | You guys are spamming and not focusing on the points I highlighted. Quoting: KingMarduk These vaccines seem to have 2 sets, one for the elite, one for the rest of us. One of them can cause issues like clots, strokes, cardiac arrest. Why is there 2 different vaccines if not for the safer one being used by the elite to convince you all to take that shit and you be given the dangerous one. BNT162b1 is even worse in term of side effects. It was withdrawn after phase I trial. The RBD only spike protein may not cause issues tested in this paper, but it causes its own problems. Elites would not take this shit without full testing on general lab rats,the common people. |
NOLAangel
User ID: 79558822 United States 03/20/2021 09:08 AM Report Abusive Post Report Copyright Violation | [link to www.mdpi.com (secure)] Quoting: KingMarduk 6. Discussion It is generally thought that the sole function of viral membrane fusion proteins is to allow the viruses to bind to the host cells for the purpose of viral entry into the cells, so that the genetic materials can be released and the viral replication and amplification can take place. However, recent observations suggest that the SARS-CoV-2 spike protein can by itself trigger cell signaling that can lead to various biological processes. It is reasonable to assume that such events, in some cases, result in the pathogenesis of certain diseases. Our laboratory only tested the effects of the SARS-CoV-2 spike protein in lung vascular cells and those implicated in the development of PAH. However, this protein may also affect the cells of systemic and coronary vasculatures, eliciting other cardiovascular diseases such as coronary artery disease, systemic hypertension, and stroke. In addition to cardiovascular cells, other cells that express ACE2 have the potential to be affected by the SARS-CoV-2 spike protein, which may cause adverse pathological events. Thus, it is important to consider the possibility that the SARS-CoV-2 spike protein produced by the new COVID-19 vaccines triggers cell signaling events that promote PAH, other cardiovascular complications, and/or complications in other tissues/organs in certain individuals (Figure 3). We will need to monitor carefully the long-term consequences of COVID-19 vaccines that introduce the spike protein into the human body. Furthermore, while human data on the possible long-term consequences of spike protein-based COVID-19 vaccines will not be available soon, it is imperative that appropriate experimental animal models are employed as soon as possible to ensure that the SARS-CoV-2 spike protein does not elicit any signs of the pathogenesis of PAH or any other chronic pathological conditions. Thanks for the info and the link. I know this but many in my family don't seem to accept this. The link seem reputable enough to convince them. |
Anonymous Coward User ID: 77952124 United States 03/20/2021 09:09 AM Report Abusive Post Report Copyright Violation | [link to www.mdpi.com (secure)] Quoting: KingMarduk 6. Discussion It is generally thought that the sole function of viral membrane fusion proteins is to allow the viruses to bind to the host cells for the purpose of viral entry into the cells, so that the genetic materials can be released and the viral replication and amplification can take place. However, recent observations suggest that the SARS-CoV-2 spike protein can by itself trigger cell signaling that can lead to various biological processes. It is reasonable to assume that such events, in some cases, result in the pathogenesis of certain diseases. Our laboratory only tested the effects of the SARS-CoV-2 spike protein in lung vascular cells and those implicated in the development of PAH. However, this protein may also affect the cells of systemic and coronary vasculatures, eliciting other cardiovascular diseases such as coronary artery disease, systemic hypertension, and stroke. In addition to cardiovascular cells, other cells that express ACE2 have the potential to be affected by the SARS-CoV-2 spike protein, which may cause adverse pathological events. Thus, it is important to consider the possibility that the SARS-CoV-2 spike protein produced by the new COVID-19 vaccines triggers cell signaling events that promote PAH, other cardiovascular complications, and/or complications in other tissues/organs in certain individuals (Figure 3). We will need to monitor carefully the long-term consequences of COVID-19 vaccines that introduce the spike protein into the human body. Furthermore, while human data on the possible long-term consequences of spike protein-based COVID-19 vaccines will not be available soon, it is imperative that appropriate experimental animal models are employed as soon as possible to ensure that the SARS-CoV-2 spike protein does not elicit any signs of the pathogenesis of PAH or any other chronic pathological conditions. Pathogenesis is the process by which a disease or disorder develops. It can include factors which contribute not only to the onset of the disease or disorder, but also to its progression and maintenance.[1] The word comes from the Greek pathos ("suffering", "disease") genesis ("creation"). i had covid 19 in jan 2021.. i was diagnosed 2 months later with vainular valve reflux issues acerbated by covid 19 and my other comorbities. i have surgery on the 25 of march where a laser will be inserted in several areas of my left leg to stop the refluxing of blood. DONT GET COVID 19 IF U CAN |
KingMarduk
(OP) User ID: 80146885 Malaysia 03/20/2021 09:14 AM Report Abusive Post Report Copyright Violation | Thanks for the info and the link. I know this but many in my family don't seem to accept this. The link seem reputable enough to convince them. Quoting: NOLAangel Here's another one, identical article but even more reputable link. [link to www.ncbi.nlm.nih.gov (secure)] |
Catseye
User ID: 80108104 Dominican Republic 03/20/2021 09:17 AM Report Abusive Post Report Copyright Violation | You guys are spamming and not focusing on the points I highlighted. Quoting: KingMarduk These vaccines seem to have 2 sets, one for the elite, one for the rest of us. One of them can cause issues like clots, strokes, cardiac arrest. Why is there 2 different vaccines if not for the safer one being used by the elite to convince you all to take that shit and you be given the dangerous one. BNT162b1 is even worse in term of side effects. It was withdrawn after phase I trial. The RBD only spike protein may not cause issues tested in this paper, but it causes its own problems. Elites would not take this shit without full testing on general lab rats,the common people. do you have a link handy? I'm trying to keep up with the info on this this study was a horrific read, I'll bet Fauci already has his "oops" speech written for later Forgive your enemies, it messes with their heads. Thoughts create, mind them well. |
anybodysguess
User ID: 73843701 United States 03/20/2021 09:27 AM Report Abusive Post Report Copyright Violation | |
TemperanceLaw
User ID: 72372974 United States 03/20/2021 09:35 AM Report Abusive Post Report Copyright Violation | You guys are spamming and not focusing on the points I highlighted. Quoting: KingMarduk These vaccines seem to have 2 sets, one for the elite, one for the rest of us. One of them can cause issues like clots, strokes, cardiac arrest. Why is there 2 different vaccines if not for the safer one being used by the elite to convince you all to take that shit and you be given the dangerous one. BNT162b1 is even worse in term of side effects. It was withdrawn after phase I trial. The RBD only spike protein may not cause issues tested in this paper, but it causes its own problems. Elites would not take this shit without full testing on general lab rats,the common people. do you have a link handy? I'm trying to keep up with the info on this this study was a horrific read, I'll bet Fauci already has his "oops" speech written for later [link to www.statnews.com (secure)] |
Gelatinous Mass
User ID: 79735739 United States 03/20/2021 09:36 AM Report Abusive Post Report Copyright Violation | |