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Anti-malarial drugs and COVID-19 --- food for thought....

 
Doommonkey
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03/05/2020 12:40 AM
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Anti-malarial drugs and COVID-19 --- food for thought....
I've seen a number of posts here recently referring to the use of chloroquine (and similar antimalarial meds) as possible agents to help treat COVID-19.....

Why, do you think, would that be effective against this particular virus? My hunch is that this thing goes inter-cellular, like the malarial-illnesses, and destroys red blood cells. That would explain the dark, nearly black blood that is being drawn from the supposedly recovered patient, that many of you have commented about. It would also help explain why the virus seems to have a second phase in which cardiac features predominate. Is there a part of this genome that has similarity to malaria? Or some other hemorrhagic fever perhaps?

As someone who suffered from a malaria-like tickborne illness, I can tell you that antimalarial drugs can be pretty harsh and also not all that effective -- and that chloroquine was taken off the market for wide use for good reason. It's a risky choice, and safer rx antimalarials exist if you have access to them.

When I was really sick with Babesia, my blood was dark, thick, and tarry -- just like the supposedly recovered patient. Malaria goes into remission and can relapse later.... so can babesia.... and apparently, so can COVID19.

There are natural supplements that are antimalarial and are safer than chloroquine, if anyone is seriously considering self medicating. Artemisinin, Cryptolepis, Quina (an herb from which quinine was derived) Andrographis....

I have no insider info to offer, no uncle-intel, not even a bioscience background ... just the perspective of someone who has been fighting against a cluster of chronic tickborne diseases, and who has done a lot of reading on treatment.
Looks like freedom but it feels like death. It's something in between I guess... it's closing time.

Lenonard Cohen
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03/05/2020 12:42 AM
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Re: Anti-malarial drugs and COVID-19 --- food for thought....
I was wondering if g6pd would protect from cvirus.

oxidative stress is not good for g6pd but genetically it offer protection from malaria.
Anonymous Coward
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03/05/2020 12:49 AM
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Re: Anti-malarial drugs and COVID-19 --- food for thought....
I've seen a number of posts here recently referring to the use of chloroquine (and similar antimalarial meds) as possible agents to help treat COVID-19.....

Why, do you think, would that be effective against this particular virus? My hunch is that this thing goes inter-cellular, like the malarial-illnesses, and destroys red blood cells. That would explain the dark, nearly black blood that is being drawn from the supposedly recovered patient, that many of you have commented about. It would also help explain why the virus seems to have a second phase in which cardiac features predominate. Is there a part of this genome that has similarity to malaria? Or some other hemorrhagic fever perhaps?

As someone who suffered from a malaria-like tickborne illness, I can tell you that antimalarial drugs can be pretty harsh and also not all that effective -- and that chloroquine was taken off the market for wide use for good reason. It's a risky choice, and safer rx antimalarials exist if you have access to them.

When I was really sick with Babesia, my blood was dark, thick, and tarry -- just like the supposedly recovered patient. Malaria goes into remission and can relapse later.... so can babesia.... and apparently, so can COVID19.

There are natural supplements that are antimalarial and are safer than chloroquine, if anyone is seriously considering self medicating. Artemisinin, Cryptolepis, Quina (an herb from which quinine was derived) Andrographis....

I have no insider info to offer, no uncle-intel, not even a bioscience background ... just the perspective of someone who has been fighting against a cluster of chronic tickborne diseases, and who has done a lot of reading on treatment.
 Quoting: Doommonkey


This was posted on 2/5 in the Solar Watch Thread. Page 3009
February 05, 2020 at 02:05:41

GAMMA RAY BURST 02-05A-20

Southern Hemisphere Constellation Pyxis (the Mariner's Compass)
 Quoting: Cosmo888


HAHAHAHA....the cure....{ Buxine is a steroid alkaloid obtained from the Buxus sempervirens, or common box tree. Buxine is identical to the much more well known 'berberine', present in Berberis vulgaris (common Barberry), also identical with bebeerine. Buxine is renown for its efficiency in easing illnesses with prominent fevers, and recommended as a substitute for quinine for treating malaria.}
 Quoting: Anonymous Coward 76777118
Anonymous Coward
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03/05/2020 12:52 AM
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Re: Anti-malarial drugs and COVID-19 --- food for thought....
Interesting thoughts OP
Doommonkey  (OP)

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03/05/2020 12:58 AM
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Re: Anti-malarial drugs and COVID-19 --- food for thought....
Thanks for reading and discussing. Malaria and babesia (as well as g6pd deficiency) can cause hemolytic anemia, which is no joke. AC may be on to something.
Looks like freedom but it feels like death. It's something in between I guess... it's closing time.

Lenonard Cohen
Doommonkey  (OP)

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03/05/2020 01:01 AM
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Re: Anti-malarial drugs and COVID-19 --- food for thought....
Also, yes ... berberine! I forgot to mention that one, but it is not only antimalarial, it is also a very potent antibacterial compound. I've been taking it for a while now. I think this virus probably requires treatment from a number of different angles (just like Lyme and coinfections does) --- treating the different components that appear to be contained within one pathogen this time around, rather than a cocktail of them....
Looks like freedom but it feels like death. It's something in between I guess... it's closing time.

Lenonard Cohen
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03/05/2020 01:05 AM
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Re: Anti-malarial drugs and COVID-19 --- food for thought....
Basically a whole list of substances g6pd should not consume are effective against malaria...and slso CV
Anonymous Coward
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03/05/2020 01:08 AM
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Re: Anti-malarial drugs and COVID-19 --- food for thought....
Sardinia island has a very large population carring different degrees of g6pd because of malaria history.

it will be interesting to see as it spread in italy how it affects sardinia.

Obviously a lot more regions have g6pd genes in the Mediterranean area and africa.
Anonymous Coward
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03/05/2020 01:15 AM
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Re: Anti-malarial drugs and COVID-19 --- food for thought....
well it seems to not be protective at all...but still eonder if a g6pd taking antioxidants would score better.


. In addition, viral particle production of G6PD-deficient cells determined by plaque assay was much higher than that of normal controls. G6PD-deficient cells were 6 and 12 fold higher in viral production than normal counterparts in fibroblasts and A549 cells at 24h post-infection, respectively. Furthermore, viral replication in G6PD-deficient cells as determined by Q-PCR was found to be 3 fold higher than normal control after approximately 10h of incubation. Taken together, these preliminary data support our hypothesis that enhanced oxidative stress in host cells renders these cells more susceptible to human coronavirus 229E infection than control cells.
Anonymous Coward
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12/03/2021 11:08 PM
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Re: Anti-malarial drugs and COVID-19 --- food for thought....
bump
Anonymous Coward
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12/03/2021 11:21 PM
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Re: Anti-malarial drugs and COVID-19 --- food for thought....
Wondering the same for quinidine, a stereoisomer of quinine.

I have bottles of Neudexta for pseudobulbar affect. It's only ingredient's are a combination of dextromethorphan/quinidine.
panther0621

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12/03/2021 11:50 PM

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Re: Anti-malarial drugs and COVID-19 --- food for thought....
watch because anti malaria drugs can mess you up. you will kill every good bacteria in your body. trust me. not cool. plus if you get something like mefloquine or taffiquine good luck not getting brain damage or killing yourself.

they military has used these drugs for the side effects and many died due to it. just be careful

no shill a poisoned vet just not wanting people to jump in and do research on whatever they put into their body





GLP