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I'm a microbiologist, (bacteriology) ask me whatever you want.

 
thinking...

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01/25/2020 06:51 PM

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Tangy, you seem educated in biology, whats your background?
 Quoting: Anonymous Coward 78344784


Seriously I am not.. I worked in veterinary medicine, vet tech, but retired at 31. 20 odd years ago.. lol

Since 2009, I have enjoyed reading and following stuff like this.
 Quoting: Tangy


Long ago, when my vets first urged me to start vaccinating my dogs for corona virus, I asked if it was absolutely necessary, due my concerns about adjuvants causing cancer. They stressed that corona in dogs was highly contagious and serious in that it could kill the dog. Did you ever come across a dog who had it?
In his poem Human Pride, Marx admits that his aim is not to improve the world, reform or revolutionize it, but simply to ruin it and enjoy it being ruined:

With disdain I will throw my gauntlet full in the face of the world,
And see the collapse of this pygmy giant whose fall will not stifle my ardor.
Then will I wander godlike and victorious through the ruins of the world
And, giving my words an active force, I will feel equal to the Creator.

“Looking for consciousness in the brain is like looking in the radio for the announcer.”

– Nasseim Haramein, Director of Research for the Resonance Project


Normalize every aberrant behavior, bring common all deviancy and let fly the reins of morality and reason, then welcome in that utopia that liberals embrace called communism, that which most Americans with but a shard of ethic would immediately recognize as evil.
 Quoting: judahbenhuer
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[link to www.9news.com.au (secure)]

?
Anonymous Coward (OP)
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01/25/2020 06:53 PM
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Re: I'm a microbiologist, (bacteriology) ask me whatever you want.
OP i have a unique question does being rh- have any benefits since we do not have the "monkey blood" does it make it more difficult for the virus to find a foothold?
 Quoting: catnahalf


Thats an interesting question which might relate to what i just posted about surface antigens/enzymes on influenza strains.

If one of the mechanisms by which this corona viruses spreads is related to blood typing then sure, different blood grouping might play a factor in immune responce to this virus, that would be entirely hypothetical though.

Personally i would speculate that since this virus appears to be a bat respiratory virus, something novel about this virus is related to respiratory tissue receptors.

Not sure exactly how this virus is spreading though, im making an asumption a primary route is via droplet inhalation and via the respiratory system, it might be biologically active in other ways, some people have suggsted it has a route in via your eyes too, which would make sense also as the skin is very thin also around the eyelids (look at your capiliaries in the mirror under your eyelid)

It could just be that the virus attachment is preferable just like any route that generally is facilitated by a thin dermis, ie the respiratory system, your eyelids both being factors factors here.
Tangy

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Re: I'm a microbiologist, (bacteriology) ask me whatever you want.
could a coronavirus that causes the common cold be engineered to trick the immune system into identifying nCoV and killing it off?

We could engineer a light form and spread it before this one takes hold making the world immune to the more virulent form.
 Quoting: Anonymous Coward 75960975


IMO yes, now they have the genome yes, the problem is mutations that affect the surface antigens that our immune system keys too, they could hypothetically isolate the genes that are responsible for the outer protein structure of the viron and use those genes to make a genetically modified harmless strain and use those antigens to create an immune responce. It might mutate too quickly that this becomes fruitless though. Hypothetically. I might be way off on this an immunologist and virologist and biochemist would help here.

In influenza strains the N H prefixes (ie h1n1) you see are generally identifying the types of hemagluttanin (sugar protein) that causes blood cell clotting and neuraminidase (enzyme that breaks sugar bonds in molecules) on the surface of those particular flu strains.

The real question is how is the immune reaction to the orginal virus and would that be benefitial, it appears to be novel, so the rumours about it caused cytokine storms might have validity.

They might honestly be better just using cultured inert viruses or antibody transfer, the problem is i dont know if they can culture this virus well yet, and antibodiy farming is time sensitive.
 Quoting: Anonymous Coward 78344784


fascinating..

related I think

[link to cepi.net (secure)]
Tangy

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01/25/2020 06:56 PM
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Re: I'm a microbiologist, (bacteriology) ask me whatever you want.
Tangy, you seem educated in biology, whats your background?
 Quoting: Anonymous Coward 78344784


Seriously I am not.. I worked in veterinary medicine, vet tech, but retired at 31. 20 odd years ago.. lol

Since 2009, I have enjoyed reading and following stuff like this.
 Quoting: Tangy


Long ago, when my vets first urged me to start vaccinating my dogs for corona virus, I asked if it was absolutely necessary, due my concerns about adjuvants causing cancer. They stressed that corona in dogs was highly contagious and serious in that it could kill the dog. Did you ever come across a dog who had it?
 Quoting: thinking...


YES.. I have seen many, mostly puppies.. it's really sad.. And has a smell all it's own.. It's survivable, but yes HIGHLY contagious, and good to protect against. I am not a fan of vaccines.
TheOracle'sCookie

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Re: I'm a microbiologist, (bacteriology) ask me whatever you want.
OP i have a unique question does being rh- have any benefits since we do not have the "monkey blood" does it make it more difficult for the virus to find a foothold?
 Quoting: catnahalf


Thought that was an interesting question, for sure.

It would appear that there IS some protection from some
of these manufactured viruses due to the fact that if
you are going to TARGET WORLD POPULATIONS the majority
of people have Rh+ blood types. It would be logical that
they wouldn't put the effort into manufacturing TWO
VIRUSES just because they couldn't really pinpoint where
in the world (except Spain for example) the Rh- blood types
lived.

I believe that Rh- blood types also have a LOWER CANCER RATE
just due to the fact that there was an actual study into
the people who contracted cancer from the POLIO VACCINES
back in the 1950's and 60's...with the Rh- blood types
having a lower infection rate. Here is a thread that
gives the report about the Cancer gene embedded in the
POLIO VACCINE. (Dr. Mary's Monkey--the recent book--will
knock your socks off in showing a connect-the-dot-link
between the exposure of this "black-ops project" to use
"weaponized cancer" to kill Castro and the assassination
of J.F.K. (who most likely was trying to stop the project.)
Wild shit.
Thread: Update Pg14 2 Trees of Genesis! Alien Covenant Ridley Scott's new Movie: Carries Message on DNA and Ark of the Covenant! Video

We'll see in this case since "all bets are OFF" with
how this was manufactured (if indeed it WAS "created"
and didn't "Mutate.")

cheers
O'sCookie

markofthebeast
FairUSE
(from "Alien Covenant" the movie.)
Anonymous Coward
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01/25/2020 06:58 PM
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Re: I'm a microbiologist, (bacteriology) ask me whatever you want.
Tangy, you seem educated in biology, whats your background?
 Quoting: Anonymous Coward 78344784


Seriously I am not.. I worked in veterinary medicine, vet tech, but retired at 31. 20 odd years ago.. lol

Since 2009, I have enjoyed reading and following stuff like this.
 Quoting: Tangy


Long ago, when my vets first urged me to start vaccinating my dogs for corona virus, I asked if it was absolutely necessary, due my concerns about adjuvants causing cancer. They stressed that corona in dogs was highly contagious and serious in that it could kill the dog. Did you ever come across a dog who had it?
 Quoting: thinking...



Never even heard of it
Anonymous Coward (OP)
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01/25/2020 06:58 PM
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Re: I'm a microbiologist, (bacteriology) ask me whatever you want.
Question I asked in another thread, but no one had an answer. Maybe someone here has a thought?

"What about the antivirals like Zovirax? I was given that a few years ago when I caught chicken pox (don't ask, please redface), the case was very light, and gone in 4 days.

Does this work on any virus, or just certain ones?"
 Quoting: Lady Jayne Smith


Zovirax is aclovir right, might be something specific about its activity against herpes viruses.
Anonymous Coward
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01/25/2020 07:00 PM
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Re: I'm a microbiologist, (bacteriology) ask me whatever you want.
Why is no one talking about this ;

[link to www.9news.com.au (secure)]
Tangy

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01/25/2020 07:00 PM
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Re: I'm a microbiologist, (bacteriology) ask me whatever you want.
OP i have a unique question does being rh- have any benefits since we do not have the "monkey blood" does it make it more difficult for the virus to find a foothold?
 Quoting: catnahalf


Thats an interesting question which might relate to what i just posted about surface antigens/enzymes on influenza strains.

If one of the mechanisms by which this corona viruses spreads is related to blood typing then sure, different blood grouping might play a factor in immune responce to this virus, that would be entirely hypothetical though.

Personally i would speculate that since this virus appears to be a bat respiratory virus, something novel about this virus is related to respiratory tissue receptors.

Not sure exactly how this virus is spreading though, im making an asumption a primary route is via droplet inhalation and via the respiratory system, it might be biologically active in other ways, some people have suggsted it has a route in via your eyes too, which would make sense also as the skin is very thin also around the eyelids (look at your capiliaries in the mirror under your eyelid)

It could just be that the virus attachment is preferable just like any route that generally is facilitated by a thin dermis, ie the respiratory system, your eyelids both being factors factors here.
 Quoting: Anonymous Coward 78344784


analysis by the Wuhan Institute team found that it enters human cells using the same doorway that SARS did. Called angiotensin converting enzyme 2 (ACE2), the door is a receptor to which a “spike protein” on the virus’s surface first attaches and then enables the virus to fuse with the host cell.

If ACE2 is “druggable,” blocking it could conceivably treat 2019-nCoV. “It should be expected and worth to test if ACE2 targeting … drugs can be used for nCoV-2019 patients,” the scientists wrote.

The genome sequences have more to give. They “will be crucially important for development of diagnostics [and] vaccines,” said biologist Richard Ebright of Rutgers University.

same link I've posted before.

[link to www.statnews.com (secure)]
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 Quoting: Anonymous Coward 76515919


He knew too much bro.
Anonymous Coward
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01/25/2020 07:01 PM
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Re: I'm a microbiologist, (bacteriology) ask me whatever you want.
Did you all see that serpent lash out like that? Not very professional for a microbiologist, now is it.

I think they are literally trying to call the "common cold" a "contagion outbreak".

Gee I wonder why they would want to do that?
 Quoting: Anonymous Coward 78342129


I detected sarcasm and responded in kind, was it warranted, probably, not, was i a bit of a dick, yeah i guess, did i offend you, perhaps, i apologise.

I'm a little annoyed that some trolls are even disputing the fact i was clearly a microbiologist tech for years. Hopefully some people with education in a relevant field come along, but i was getting frustrated with the bad information in other threads so i made this one.

I will restate the fact i am not an expert, do not take my opinion as gospel, people should research their own sources and i am not a virologist, an immunologist, a doctor, a post graduate in microbiology and was nothing more than a lab tech.

That being said, we dont know how bad this is, potentially it could be bad, i hope it isnt, but i dont trust the chinese authorities on this so far, their crackdown is probably a good thing, but have they acted too late and in a heavy handed manner in the wrong direction when they should perhaps close the damned airports for a week instead if its as serious as they are acting.
 Quoting: Anonymous Coward 78344784


You are obviously legit. I believe you. I have a degree in biochemistry and would also have one in cellular biology if I had taken just one additional credit of field biology lab. Started my career 30 years ago in public health, including having our own micro' lab and doing epidemiology. I also believe Dr. Fiegl-Ding's warnings. This one is different and has great potential for pandemic. Many more are going to become ill and at least 3% are going die. I left my office within 30 minutes of the confirmed case in Seattle to buy surgical masks at Walgreens in case me or my employees need them. They had about 100 in stock. I bought 75.
Anonymous Coward (OP)
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Do you think Hong Kong Phooey can save China and the planet?
 Quoting: Anonymous Coward 77190242


hong kong phooey, number 1 super guy, quicker than the human eye? not seen that show since i was a kid, i recall him being inept, wasnt the cat the real hero of the show?
Justmeok

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01/25/2020 07:01 PM

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Re: I'm a microbiologist, (bacteriology) ask me whatever you want.
Thanks for offering your expertise.

My questions:

1) Some have speculated that this virus accidentally escaped from the Wuhan level 4 Bio-lab. If true, and this is a bio-weapon, would it be reasonable to assume the Chinese also developed an antidote or vaccine?
If not, how long to develop a vaccine (or treatment), would you estimate?

2) Spanish has only 1 "n". sorry, that wasn't a question.

3) Seems to me that there is no chance to stop this disease if it spreads like a common cold. Is there a scenario where this can be stopped at this point? Supposedly these viruses mutate a lot. But would those mutations simply dead-end and the initial dangerous strain prevail since it is the more successful variant?

4) I have heard that the serious cases include a polio like paralysis. (perhaps explaining the video of a man doing a face plant on the sidewalk. Does it have a polio like paralysis effect? or is this simply a function of each individual's immune system as to whether it conducts an autoimmune attack on one's oown nerves?

5) This is supposedly adept at jumping species. Is there a list of other species that can carry and transmit the virus? And another list of species that can't?

6) If China has a cure or a vaccine, do you think they would withhold it to save face? Or maybe with hold it for a credible amout of time, then announce their "breakthrough". :)

Last Edited by JustmeTX on 01/25/2020 07:07 PM
Justme
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01/25/2020 07:03 PM
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Re: I'm a microbiologist, (bacteriology) ask me whatever you want.
now they are saying that Ulcers are caused by bacteria.
Question: how can these bacteria live in Hydrochloric Acid,
and how do these bacteria eat away the stomach causing
the typical open lesions of Ulcers?
 Quoting: Anonymous Coward 76809044


helicobacter pylori, i think the guy who discovered it was the caustive agent behind stomach ulcers was laughed at when he originally suggested it.

you should look into extremophiles, a lot of the enzymes and such used in dna technology were harvested from bacteria that live in volcanic, chemically extreme, very hot highly acidic and alakline environments, its why a lot of scientists think life on other planets might not be that far fethed because if life can survive in those places it really has a shot on the geothermal vents of distant solar system moons.

As for how h.pylori is an issue, pretty sure your stomach has mucus producing cells called goblet cells and the bacteria can survive in the mucus your goblet cells produce, safe from the acid,# and then cause inflamation behind the mucus in the stomach cells, some medications that act on histamine production in your stomach mediate the production of mucus.
 Quoting: Anonymous Coward 78344784


IIRC (and I may not!), the bacterial cause of stomach ulcers was suspected by a british/aus(?) common or garden GP.

To prove his theory, he infected himself with the bacteria and soon developed stomach ulcers. He promptly treated himself with antibiotics and cured it.

Brave guy. Deserves a medical oscar!
Anonymous Coward (OP)
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Re: I'm a microbiologist, (bacteriology) ask me whatever you want.
You're quite knowledgeable with a good sense of humor & honesty about yourself, all the best to you, OP! Oh, about 25 fingertipped callous's worth...))

hf
 Quoting: Anonymous Coward 76775164


cant believe that guy used to play heavy gauge strings like 11's and 12's, shame he died.
Tangy

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01/25/2020 07:04 PM
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Why is no one talking about this ;

[link to www.9news.com.au (secure)]
 Quoting: Anonymous Coward 76515919


Not sure, but it sounds like he was more working on global medical care for all, rather than testing or discovering disease. I may be wrong.. For many years there have been mysterious deaths. My brain is 9823734 different directions right now. What was the cause of death?

Last Edited by Tangy on 01/25/2020 07:07 PM
ThirstyMarlin

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Do you think Hong Kong Phooey can save China and the planet?
 Quoting: Anonymous Coward 77190242


hong kong phooey, number 1 super guy, quicker than the human eye? not seen that show since i was a kid, i recall him being inept, wasnt the cat the real hero of the show?
 Quoting: Anonymous Coward 78344784


Marlin!
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Re: I'm a microbiologist, (bacteriology) ask me whatever you want.
Best home remedies for neutralizing cytokine storm...?

Theive's oil (mixture)? Other oils? Heavy dosage of Vitamin C serum?

Something else...?

TIA...
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Vena Sera
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Re: I'm a microbiologist, (bacteriology) ask me whatever you want.
Is this behaving like a man made bio weapon ?
So,if this is designed to kill,live outside,infect easily no initial symptoms, we seem to be fucked.
 Quoting: Black Diamond 77083188


Evolution has had billions of years to make its own bioweapons, we act like we are in charge but we are always at the whims of the micro organisms so to speak, we dont need a bioweapon to fuck us, nature is perfectly capable of doing that, we have been long overdue a disease on the scale of the spannish flu imo.

Is this a bioweapon, i dont know, if i made a bioweapon a highly contagious common cold like virus with a fatality rate not too high to facilitate spread and a highly infectious non symptomatic phase would be my go too. It does seem convenient tbh, but evolution always finds a niche, as i said, we have been long naturally overdue something like this.
 Quoting: Anonymous Coward 78344784


Sigh

This is incorrect
Lady Jayne SmithModerator
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01/25/2020 07:05 PM

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Re: I'm a microbiologist, (bacteriology) ask me whatever you want.
Question I asked in another thread, but no one had an answer. Maybe someone here has a thought?

"What about the antivirals like Zovirax? I was given that a few years ago when I caught chicken pox (don't ask, please redface), the case was very light, and gone in 4 days.

Does this work on any virus, or just certain ones?"
 Quoting: Lady Jayne Smith


that is specific to that virus only....varicella zoster
 Quoting: Bird Shadow


Thank you hf
Fate whispers to the warrior

"You cannot withstand the storm"

the warrior whispers back

"I am the storm"

INTJ-A

Killer Bunny
Anonymous Coward (OP)
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01/25/2020 07:08 PM
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Re: I'm a microbiologist, (bacteriology) ask me whatever you want.
long story, making short, i have to put a prescription in my nose the first 5 days of the month as i am a 'staph' carrier, i recently had a skin issue and a guy from India whom i didnt quite understand handed me a note that said, Kalonji (Nigella Seeds),, and go to the local Thai market and start taking, i put 5/6 seeds in water and drink in am, my skin is completely healed, asking OP, have you heard of this, and is it a good recommendation for others? as a preventative? i recently ordered the caps on Amazon. stay safe all, ty
 Quoting: 71cuda 78330135


no im afraid.
Sungaze_At_Dawn

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01/25/2020 07:10 PM

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Re: I'm a microbiologist, (bacteriology) ask me whatever you want.
So how often do you do partisan research and partisan facts?

ie. this lovely new virus. Anyone questioned you about it and the hype around it?


Do you find it odd that its emerged for the senate trial? Is scientific funding often a political motivated arena?

Do you think mutation is something that enhances a virus or does it, just water it down like it did with the Swine flu?

Many of us aren't buying the hype, it looks like a mortality rate similar to the flu.

How do you think it will compare to the common cold/flu pneumonia rates?

Last Edited by Sungaze_At_Dawn on 01/25/2020 07:11 PM
The Devil tries to convince everyone he doesn't exist.
The state tries to convince everyone they cannot resist.
Do not go quietly into the good night. Rage Rage against the dying light!
Anonymous Coward (OP)
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01/25/2020 07:11 PM
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Re: I'm a microbiologist, (bacteriology) ask me whatever you want.
but I'v seen the hemorrhaging in the videos...haven't you? look at 55 seconds in (this is one of the more noticeable hemorrhaging examples)


 Quoting: Wildthing3


Way to early to speculate whats going on here, i dont know if the blood was from a head injury here or what is going on, we dont have any info on if these people were immune compromised or had issues like asthma, copd etc.
Anonymous Coward (OP)
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01/25/2020 07:15 PM
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Re: I'm a microbiologist, (bacteriology) ask me whatever you want.
Long ago, when my vets first urged me to start vaccinating my dogs for corona virus, I asked if it was absolutely necessary, due my concerns about adjuvants causing cancer. They stressed that corona in dogs was highly contagious and serious in that it could kill the dog. Did you ever come across a dog who had it?
 Quoting: thinking...


thats a good question, i like the thinking here, i think corona viruses are dangerous to cats also.
Anonymous Coward
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01/25/2020 07:17 PM
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Re: I'm a microbiologist, (bacteriology) ask me whatever you want.
Did you all see that serpent lash out like that? Not very professional for a microbiologist, now is it.

I think they are literally trying to call the "common cold" a "contagion outbreak".

Gee I wonder why they would want to do that?
 Quoting: Anonymous Coward 78342129


I detected sarcasm and responded in kind, was it warranted, probably, not, was i a bit of a dick, yeah i guess, did i offend you, perhaps, i apologise.

I'm a little annoyed that some trolls are even disputing the fact i was clearly a microbiologist tech for years. Hopefully some people with education in a relevant field come along, but i was getting frustrated with the bad information in other threads so i made this one.

I will restate the fact i am not an expert, do not take my opinion as gospel, people should research their own sources and i am not a virologist, an immunologist, a doctor, a post graduate in microbiology and was nothing more than a lab tech.

That being said, we dont know how bad this is, potentially it could be bad, i hope it isnt, but i dont trust the chinese authorities on this so far, their crackdown is probably a good thing, but have they acted too late and in a heavy handed manner in the wrong direction when they should perhaps close the damned airports for a week instead if its as serious as they are acting.
 Quoting: Anonymous Coward 78344784


I am a lab tech. I work in a microbiology lab.
That doesn’t make me a fucking microbiologist
You are probably just a bench tech that plates throat swabs and shit
Anonymous Coward (OP)
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01/25/2020 07:20 PM
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Re: I'm a microbiologist, (bacteriology) ask me whatever you want.
analysis by the Wuhan Institute team found that it enters human cells using the same doorway that SARS did. Called angiotensin converting enzyme 2 (ACE2), the door is a receptor to which a “spike protein” on the virus’s surface first attaches and then enables the virus to fuse with the host cell.
 Quoting: Tangy


That makes total sense, im loosely aware of angiotensin, my immunology is real rusty too these days.

But something targeting its attachment would be a good cure/prevention as i alluded. Ill have to read up on that mechanism and its simularity to the SARs mechanism.
Anonymous Coward
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01/25/2020 07:21 PM
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Re: I'm a microbiologist, (bacteriology) ask me whatever you want.
What's your endgame OP. We we are Fragged why not just come out and say it.
ThirstyMarlin

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01/25/2020 07:21 PM
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Re: I'm a microbiologist, (bacteriology) ask me whatever you want.
The best way to "beat" any bacteria or virus is to simply have a healthy immune system. All this talk of special nutrition and or exotic cures is just bull crap.

The human body is amazing, and can defeat anything thrown at it...if you are healthy and get plenty of sleep.

This includes everything from cancer to the common cold.

But, there is another crucial step to make this work. You need to catch a very low 'dose' of the intruder and then get plenty of sleep and water. Rest will cure a tremendous amount of ailments of this type. While sleeping, the body can battle the intruders, and with unknown invaders, it will take a little time to figure out how to kill this unique infiltrator.

The problem is, in modern society, people don't have enough time to sleep through an invasion. Jobs, family, and other needs force us to get up and therefore not be in bed. And when I suggest being in bed and/or asleep...I mean for a week; possibly more. Do that, and your immune system will figure out how to kill the intruder and from then on it will be easy to defeat that particular attack.

Rest, sleep, and water + a catching a low dose of the invasion works, but a sudden heavy dose of infection will overwhelm the immune system.

I guess on this thread we all have our ideas on how to deal with the common cold, because that is what this is, a super-charged common cold. The very young and elderly will have trouble. Everyone who is working too hard will have trouble. But just watch, some people will have no problem. Why?
Kermit puke
Marlin!





GLP