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Smoking Gun; what does USAMRIID research say about aerosolized Ebola Zaire? | |
| emerald eye
Keeping an "eye out" for the truth.  User ID: 39877195  United States10/03/2014 08:41 PM  Report Abusive Post Report Copyright Violation | Guess who scientifically proved and published that lethal infections in primates can be caused by aerosolized Ebola Zaire? USAMRIID Who is the United State Army Medical Research Institute of Infectious Diseases? “Since 1969, USAMRIID has served as the Department of Defense's (DoD) lead laboratory for medical biological defense research. While our core mission is to protect the warfighter from biological threats, we also investigate disease outbreaks and threats to public health. [link to www.usamriid.army.mil] The United State Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, USA published the following scientific study and paper in 1995: “Lethal experimental infections of rhesus monkeys by aerosolized Ebola virus.” I wasn't going to post this here, because I didn't want to make people more afraid than they already are, but they deserve to know the truth. The shocking disregard of our criminal government for the health of its citizens, the insane behavior of the CDC, and other governmental agencies, and inappropriate laxity of the airline industry, along with the almost willful encouragement of Ebola to be seeded to the US and elsewhere have changed my mind. Please download this PDF before it “disappears”. “Lethal experimental infections of rhesus monkeys by aerosolized Ebola virus” “E. JOHNSON, N. JAAX, J. WHITE AND P. JAHRLING” “United State Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, USA” “Received for publication 13 January 1995” “Accepted for publication 24 May 1995” "Discussion: This study demonstrates aerosol transmission of Ebola virus to non-human primates. Inhalation doses as low as 400 PFU of virus caused a fatal illness clinically similar to that previously reported for monkeys infected by parenteral inoculation (Baskerville et a/. 1978; Bowen et at. 1978; Fisher-Hoch et a/. 1985). The illness was characterized by fever, anorexia and a petechial rash. Fibrin deposition and fibrin thrombi throughout the vascular system in all monkeys suggested that disseminated intravascular coagulation (DIC) may have also played a role in the clinical manifestations of Ebola virus infection. Our aerosol infectivity findings for Ebola virus support Dalgard's and Pokhodyaev's observations that suggested a role for aerosol transmission of filoviruses in monkeys. Epidemiology studies of human disease outbreaks in sub-Saharan Africa did not suggest that aerosol transmission of filoviruses was likely in that setting." “Although coughing was common among the human Ebola haemorrhagic fever cases in Africa, there was no direct evidence for the aerogenic spread of Ebola virus in human populations. Several potential explanations might account for this situation. It is possible that the quantity and distribution of the virus within most patient’s respiratory tracts may have been below the level needed to establish effective aerosol transmission. “ “We also demonstrated aerosol transmission of Ebola virus at lower temperature and humidity than normally present in sub-Saharan Africa. Ebola virus sensitivity to the high temperatures and humidity in the thatched, mud and wattle huts shared by infected family members in southern Sudan and northern Zaire may have been a factor limiting aerosol transmission of Ebola virus in the African epidemics." "Both elevated temperate and relative humidity (RH) have been shown to reduce the aerosol stability of viruses (Songer 1967). Our experiments were conducted at 24 degrees C and less than 40% RH, conditions which are known to favor the aerosol stability of at least two other African haemorrhagic fever viruses, Rift Valley fever and Lassa (Stephenson et al. 1984; Anderson et al 1991)." "If the same holds true for filo viruses, aerosol transmission is a greater threat in modern hospital or laboratory settings than it is in the natural climatic ranges of viruses. The route of infection, or the degree of the pulmonary involvement of the primary cases may also be an important factor to consider when evaluation the natural aerosol transmissibility of the filoviruses." "While both parenteral and aerosol exposure to Ebola virus causes systemic disease involving all organs, monkeys exposed to the viral aerosols during our study developed strong immunoreactivity for Ebola Virus antigen in airway epithelium. In oral and nasal secretions, and in bronchial and tracheobronchial lymphoid tissue. By electron microscopy, viral replication after aerosol exposure occurred in the lungs and tracheobronchial lymph nodes, and extracellular virus accumulated in alveoli of the lung." "Copious extracellular Ebola virus antigen was present in secretions on the mucosal surfaces of the nose, oral cavity and pulmonary airways of aerosol exposed monkeys, strong evidence to support the potential for secondary spread of Ebola virus by aerosol. As previously stated, aerosol spread was implicated in the spread of disease among the monkeys at Reston (Dalgard et al. 1992; Geisbert 1992) and may have occurred between monkeys and animal handlers who were in close contact with infected monkeys (CDC 1990)" "Finally, host sensitivity to filovirus infections may also be a significant factor influencing the degree of aerosol transmissibility Asian (Macaca fascicularis) and African (Cercopithecus aethiops) monkeys know to be disseminating hosts for filoviruses (Gear et al 197; CDC 1990). Virus replicates extensively in Ebola virus infected non-human primates, reaching high concentrations in tissues (consistently greater than 6 log 10/g of tissue or serum for Reston virus,; P. Jahrling unpublished). Quantitate data for viraemia levels in humans are lacking as are estimates of minimal infections aerosol doses. Certainly filoviruses have infected humans with no known history of parenteral or ocular inoculation of the viruses. (Martini 1971; CDC 1990) and a respiratory route of infection cannot be rule out (Simpson 1977). Those cases may have resulted from exposures to unusual concentrations of aerosolized virus not often encountered naturally. In that regard, retrospective examination of any available archived human tissues by immunocytochemistry could prove to be helpful. “ "Regardless, we have shown that Ebola virus (Zaire strain) can be transmitted by aerosol in an experimental primate model. In light of the pathogenicity of human filovirus infections, health care personnel at risk of exposure should use precautions to minimize the risk of aerosol exposure while managing acutely ill haemorrhagic fever cases of unknown or filoviral etiology. The risk can be markedly reduced by adhering to sound and practical infectious disease management procedures. This requires curtailing aerosol generating procedures; using protective clothing including gloves and masks, adequately decontaminating potentially infectious material, and conducting viral diagnostic procedures in regional containment facilities capable of safely handling highly hazardous infectious agents (Comperts et al 1978; CDC 1988).” [link to www.ncbi.nlm.nih.gov] (Less than 50% quoted as per GLP policy) So the bottom line here; in my opinion, is that the CDC is basing its current recommendations on epidemiologic studies from a different climate and environment, while the US army research shows scientifically and conclusively that aerosolized Ebola Zaire transmission is possible in primates, and is probably more likely to occur in a colder and less humid environment than exists in Africa. Guess what, we are heading into the cold dry months throughout the northern hemisphere with far less UV (sunlight) than in equatorial Africa. We know that UV light to some degree inactivates most viruses, including the Ebola and Lassa viruses, specifically the 254 nm wavelength. “The data obtained indicate that the UV resistance of Lassa virus is higher than that of Ebola virus. The UV sensitivity of vaccinia virus (a surrogate for variola virus) appeared intermediate between that of the two virulent viruses studied. [link to nihbrp.com] Here is a good paper on preventing the aerosolized transmission of the H1N1 virus. [link to www.dtic.mil] Good luck to us all, be smart, and be safe.  Courage forges a path through all obstacles, while fear is the obstruction of all dreams. The only way that anyone gets something for nothing, is that someone else has given up something for nothing. |
| emerald eye
(OP) Keeping an "eye out" for the truth. User ID: 39877195 United States10/03/2014 09:00 PM Report Abusive Post Report Copyright Violation | This paper involves one of the Ebola virus subgroups, Reston. The Reston Ebola virus was named after Reston Virginia. In Reston Virginia there was a near miss, when a primate research facility had a type of Ebola burn through its facility. Reston seems to be unique, because although it killed monkeys with ease, it did not appear to cause a fatal disease in humans. Nonetheless, it is still considered an Ebola virus, and in fact is thought to have possibly descended from Ebola Zaire as a mutation. “Most recent common ancestry can be traced back only within the last 50 years for Reston ebolavirus and Zaire ebolavirus species and suggests that viruses within these species may have undergone recent genetic bottlenecks.” [link to jvi.asm.org] “Ebola Reston Virus Infection of Pigs: Clinical Significance and Transmission Potential” “Ebola virus (EBOV) and the closely related Marburg virus (MARV) belong to the family Filoviridae. They are enveloped, filamentous, negative-sense RNA viruses and may be associated with severe zoonotic disease in humans. Currently, 4 species of EBOV have been reported: Zaire ebolavirus (ZEBOV), Sudan ebolavirus (SEBOV), Ivory Coast ebolavirus, and Reston ebolavirus (REBOV) [1]. A fifth species, Bundibugyo ebolavirus, has been proposed [2]. Four species of EBOV have caused fatal disease in humans with mortality rates of 50%–90% depending on virus strain [3, 4]. In contrast, REBOV has never been identified to cause disease in people.” “From September 2007 to May 2008, disease outbreaks were reported on several pig farms in the Philippines. Pigs of all ages were affected, with a wide variety of clinical signs of disease including fever, coughing, and skin lesions.” “In addition, REBOV was isolated from lung and lymph nodes of pigs from each of the 3 farms. Full genome sequences were obtained for each of the REBOV isolates, with distinct sequences from each location showing approximately 4% nucleotide difference in sequence identity between isolates and no discernable grouping with the REBOV isolates obtained from macaques. The differences in swine isolates suggest distinct spillover events from an as yet unidentified host or that pigs act as asymptomatic hosts with virus circulating in them for many years. Bats have been implicated as reservoirs for filoviruses in Africa, including ZEBOV and MARV, and further investigations are necessary to determine whether REBOV is present in bats in the Phillipines. In addition to evidence of infection in swine, 141 people were also tested for the presence of antibodies to REBOV. Six individuals tested positive for immunoglobulin G (IgG), all of whom worked on pig farms or with swine products, suggesting the potential transmission from pigs to humans.” “In study 1, REBOV genome was detected in nasopharyngeal secretions of pigs from 2 to 8 days following exposure by the oronasal route (Table 1), with virus reisolated from days 4 to 8 after infection.” In other words, virus was detected following exposure by the oral or nasal route in pigs 2-8 days after known infection. Virus could be cultured from the nasal secretions 4-8 days after exposure. “Following exposure of 5-week-old pigs, REBOV replication was confirmed in many tissues. The highest levels of virus replication were observed in lung and lymphoid tissue, the tissues from which virus was isolated in the original disease investigation. Virus isolation was also performed on muscle tissue with infectious virus being isolated from 6 of the 8 pigs in the second study. The infection profiles were consistent with an acute infection, with virus clearance associated with seroconversion occurring within 10–12 days after challenge.” In other words, the infected animals showed virus replication in the lung and lymph tissue, at 4-8 days after infection, but did not initially test positive for Ebola Reston, it took 10-12 days for the tests to become positive, even though infection had been present for 10-12 days. “Shedding of virus was identified most consistently via the nasopharynx, suggesting that this might provide a route of transmission by contact (aerosol or droplet) from pig to pig, which may be facilitated if concurrent respiratory disease is present. Shedding via the fecal route was observed in some circumstances and this may provide additional sources of contamination or transmission.” In other words, the virus was easily shed through the oral and nasal cavity, suggesting aerosol or droplet transmission, which could be enhanced if other respiratory diseases were present. “It is possible, although clearly unproven, that a higher prevalence of subclinical respiratory infections in the winter may have predisposed this cohort to a more florid infection with REBOV. Mycoplasma may predispose animals to enhanced REBOV replication as increased populations of alveolar macrophages may support higher levels of virus replication, Unfortunately, lack of capability for identification of nonviral pathogens at BSL4 currently precludes detailed examination of such interactions.” [link to jid.oxfordjournals.org] In other words, other types of respiratory infections in pigs might have enhanced the prevalence of Ebola Reston respiratory infections. Because Ebola is considered a BSL4 pathogen, it is only studied under very restrictive circumstances. We don’t have a lot of scientific data for how it behaves in the real world outside of Africa. Also winter cold and flu season is coming. The CDC appears to be making recommendations based upon African epidemiology rather than known science about viruses. There is so much that we do not know about these filo viruses and how they will behave in other climates, and with other mitigating factors such as colds and flu and other infections that occur in the fall and winter in the Northern Hemisphere. This is much to important to be guessing about. Last Edited by emerald eye on 10/03/2014 09:04 PM Courage forges a path through all obstacles, while fear is the obstruction of all dreams. The only way that anyone gets something for nothing, is that someone else has given up something for nothing. |
| emerald eye
(OP) Keeping an "eye out" for the truth. User ID: 62374069 United States10/03/2014 10:44 PM Report Abusive Post Report Copyright Violation | I know that these papers are a little hard to understand for someone who is not familiar with scientific literature. That is why I have tried to break these papers down a bit. When the CDC says that Ebola Zaire is only transmitted by close bodily contact or contact with bodily fluids, they are picking and choosing, and basing those statements and making those recommendations upon what is known about the African epidemiology of this virus rather than known science about viruses. “The filoviruses, Marburg and Ebola, are classified as Category A biowarfare agents by the Centers for Disease Control. Most known human infections with these viruses have been fatal, and no vaccines or effective therapies are currently available. Filoviruses are highly infectious by the airborne route in the laboratory, but investigations of African outbreaks have shown that person-to-person spread requires direct contact with virus-containing material.” [link to courses.washington.edu] There is a cave in on the border of Uganda and Kenya in Mount Elgon National park called Kitum cave that is thought to be sort of a ground zero for Marburg. Several people have inexplicably become infected while visting the cave, which is home to many bats, thought to be an intermediate host to Marburg. Of course the cave is loaded with bat feces. “In 1980 other cases were discovered, one in Western Kenya not far from the Ugandan source of the monkeys implicated in the 1967 outbreak. The patient had visited Kitum Cave in Kenya's Mount Elgon National Park. The patient's attending physician in Nairobi became the second case; he recovered.” “Another human Marburg infection was recognized in 1987 when a 15-year-old Danish boy who had traveled extensively in Kenya, including western Kenya, became ill and later died. Prior to the infection, he too, like the 1980 victim, had visited Kitum Cave.” [link to www.globalsecurity.org] In addition to caves, there have also been outbreaks of Marburg virus disease in mines: “Uganda’s rapid response to the recent fatal Marburg haemorrhagic fever outbreak not only stopped the spread in its tracks, but also raised hopes the discovery of the disease’s reservoir, possibly in a bat-infested jungle mine.” “The 30 July confirmation was, at that time, the latest in a chain of actions initiated by Ugandan authorities to contain what investigators suspected was a rare outbreak of Marburg haemorrhagic fever.” “The disease emerged in two labourers who worked at a gold and lead mine in the western Ugandan jungle. One miner died on 14 July, while the other remains in quarantine. The two are the outbreak’s only confirmed cases.” [link to www.who.int] “A total of 154 cases (48 laboratory-confirmed and 106 suspected) were identified (case fatality rate, 83 percent); 52 percent of cases were in young male miners. Only 27 percent of these men reported having had contact with other affected persons, whereas 67 percent of patients who were not miners reported such contact (P<0.001).Most of the affected miners (94 percent) worked in an underground mine. Cessation of the outbreak coincided with flooding of the mine. ” “The findings imply that reservoir hosts of Marburg virus inhabit caves, mines, or similar habitats.” [link to www.ncbi.nlm.nih.gov] "Sunlight or, more specifically, solar UV radiation (UV) acts as the principal natural virucide in the environment. UV radiation kills viruses by chemically modifying their genetic material, DNA and RNA. The most effective wavelength for inactivation, 260 nm (55), falls in the UVC range, so-named to differentiate it from near-UV found in ground-level sunlight, i.e., the UVB and UVA portions of the spectrum, 290 to 320 nm and 320 to 380 nm, respectively (51). Nucleic acids are damaged also by UVB and UVA but with lower efficiency than by UVC radiation [link to jvi.asm.org] [link to jvi.asm.org] Now imagine, that a type of virus (a Filovirus), is kept in check in its natural habitat in the tropics by its natural enemies of sunshine, warm temperatures, and humidity year around. When it gets a foothold it burns out, mostly due to a climate that is mostly inhospitable to its needs for cool, dark and damp, rather than any paltry human efforts to contain it. In that warm sunny climate the virus is mostly limited to transmission by blood, body fluids and close contact, because it is rapidly inactivated by sunlight, heat and the higher humidity limits its airborne transmission. Now imagine that it is able to hop a plane to a new, and much friendlier environment. One that is cold, dark and less damp for at least 5-8 months out of the year. One that doesn’t as effectively inhibit aerosol or airborne transmission because the air is cool and dry and there isn’t much sunlight. The virus stays viable much longer in this environment. Along with that, people are coughing from colds and flu viruses, and this filovirus has the opportunity to be present right alongside in nasal secretions, with every cough and sneeze. We have now possibly liberated a monster by allowing it to hitch a ride on planes to a new ecosystem and possibly friendlier one. This is what this post is really about. Like I said before, there is so much that we do not know about these filo viruses and how they will behave in other climates, and with other mitigating factors such as colds and flu and other infections that occur in the fall and winter in the Northern Hemisphere. This is much to important to be guessing about. Last Edited by emerald eye on 10/03/2014 11:33 PM Courage forges a path through all obstacles, while fear is the obstruction of all dreams. The only way that anyone gets something for nothing, is that someone else has given up something for nothing. |
| Anonymous Coward User ID: 39931345 United States10/03/2014 10:54 PM Report Abusive Post Report Copyright Violation | |
| Thetruthmonger
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| Anonymous Coward User ID: 3694399 United States10/03/2014 10:57 PM Report Abusive Post Report Copyright Violation | |
| TerrorByte
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| nilla
User ID: 55722629 United States10/03/2014 11:08 PM Report Abusive Post Report Copyright Violation | |
| emerald eye
(OP) Keeping an "eye out" for the truth. User ID: 62374069 United States10/03/2014 11:08 PM Report Abusive Post Report Copyright Violation | Thanks, and thanks for the pin. I just don't want people to be caught off guard, believing the "party line" and not protecting themselves properly. The CDC can legally say the things that they are saying about transmission, because they are basing it upon the transmission epidemiology that has been observed in Africa, so essentially they are telling somewhat of the truth. The problem is that the epidemiology in the lab may be different, and that lab environment seems to coincide more closely to hospitals, planes, office buildings, subways, and the northern hemisphere in winter. A new epidemiology may evolve due to a new environment, and I don't think that we can necessarily extrapolate the African epidemiology for the Northern Hemisphere entering fall and winter. We are safer extrapolating the lab data and being abundantly cautious, rather that optimistically careless. Regards to all and stay safe. PS I am sorry there was so much text, but I could explain it in a credible way without it. Courage forges a path through all obstacles, while fear is the obstruction of all dreams. The only way that anyone gets something for nothing, is that someone else has given up something for nothing. |
| Anonymous Coward User ID: 63276700 United States10/04/2014 12:18 AM Report Abusive Post Report Copyright Violation | some rna viruses: Ebola hemorrhoragic fever, SARS, influenza, hepatitis C, West Nile fever, common cold, polio and measles. all of these have been hyped in the past several years, except hep-c. all of those have been weaponized at some point. |
| #521
User ID: 28730804 United States10/04/2014 12:22 AM Report Abusive Post Report Copyright Violation | |
| TeamReaper
User ID: 22030141 United States10/04/2014 12:40 AM Report Abusive Post Report Copyright Violation | Great research!! Check out and read this book, details the 1989 Reston, VA lab Ebola incident where it spread via air ducts: The Hot Zone [link to www.amazon.com] Last Edited by TeamReaper on 10/04/2014 12:41 AM In every operation, whether planning it or executing it, you can never count on luck; but you have to accept it, and recognize it when it’s there. -Major ******, U-2 Pilot/Instructor/Flight Commander |
| Anonymous Coward User ID: 47078040 United States10/04/2014 12:48 AM Report Abusive Post Report Copyright Violation | |
| my2centsworth
User ID: 63300102  Canada10/04/2014 12:59 AM Report Abusive Post Report Copyright Violation | |
| Anonymous Coward User ID: 47078040 United States10/04/2014 01:00 AM Report Abusive Post Report Copyright Violation | some rna viruses: Ebola hemorrhoragic fever, SARS, influenza, hepatitis C, West Nile fever, common cold, polio and measles. Quoting: Anonymous Coward 63276700 all of these have been hyped in the past several years, except hep-c. all of those have been weaponized at some point. Weaponization is the one thing the OP did NOT mention. Using nanoparticulates to carry a virus, or a toxin, is one way deliver them. They are able to stay airborne for long periods of time, and can be released from aircraft. |
| Anonymous Coward User ID: 9019067 United States10/04/2014 01:06 AM Report Abusive Post Report Copyright Violation | Thanks, and thanks for the pin. Quoting: emerald eye I just don't want people to be caught off guard, believing the "party line" and not protecting themselves properly. The CDC can legally say the things that they are saying about transmission, because they are basing it upon the transmission epidemiology that has been observed in Africa, so essentially they are telling somewhat of the truth. The problem is that the epidemiology in the lab may be different, and that lab environment seems to coincide more closely to hospitals, planes, office buildings, subways, and the northern hemisphere in winter. A new epidemiology may evolve due to a new environment, and I don't think that we can necessarily extrapolate the African epidemiology for the Northern Hemisphere entering fall and winter. We are safer extrapolating the lab data and being abundantly cautious, rather that optimistically careless. Regards to all and stay safe. PS I am sorry there was so much text, but I could explain it in a credible way without it. Dunno about you but a stash of proper reverse transcriptase inhibitor, in addition to endorphin amplification regimen and some extra vitC and multivits are about all you can do besides oral k replacement solution, d5lr iv and a house full of uv lamps and cases of pool bleach along with easily prepared food stored at home would seem to be words to the wise. It should go without saying that there is a reliable cure or treatment available given the intentionally incompetent manner this is being dealt with. |
| IM YOUR HUCKLEBERRY
User ID: 39291766 United States10/04/2014 01:12 AM Report Abusive Post Report Copyright Violation | |
| Anonymous Coward User ID: 9019067 United States10/04/2014 01:13 AM Report Abusive Post Report Copyright Violation | some rna viruses: Ebola hemorrhoragic fever, SARS, influenza, hepatitis C, West Nile fever, common cold, polio and measles. Quoting: Anonymous Coward 63276700 all of these have been hyped in the past several years, except hep-c. all of those have been weaponized at some point. Weaponization is the one thing the OP did NOT mention. Using nanoparticulates to carry a virus, or a toxin, is one way deliver them. They are able to stay airborne for long periods of time, and can be released from aircraft. Thats why large uv lamps have to be positioned at every entrance/exit and why intake air must be filtered and uv exposed. Duct tape and plastic will become important. |
| emerald eye
(OP) Keeping an "eye out" for the truth. User ID: 62374069 United States10/04/2014 01:28 AM Report Abusive Post Report Copyright Violation | Thanks, and thanks for the pin. Quoting: emerald eye I just don't want people to be caught off guard, believing the "party line" and not protecting themselves properly. The CDC can legally say the things that they are saying about transmission, because they are basing it upon the transmission epidemiology that has been observed in Africa, so essentially they are telling somewhat of the truth. The problem is that the epidemiology in the lab may be different, and that lab environment seems to coincide more closely to hospitals, planes, office buildings, subways, and the northern hemisphere in winter. A new epidemiology may evolve due to a new environment, and I don't think that we can necessarily extrapolate the African epidemiology for the Northern Hemisphere entering fall and winter. We are safer extrapolating the lab data and being abundantly cautious, rather that optimistically careless. Regards to all and stay safe. PS I am sorry there was so much text, but I could explain it in a credible way without it. Dunno about you but a stash of proper reverse transcriptase inhibitor, in addition to endorphin amplification regimen and some extra vitC and multivits are about all you can do besides oral k replacement solution, d5lr iv and a house full of uv lamps and cases of pool bleach along with easily prepared food stored at home would seem to be words to the wise. It should go without saying that there is a reliable cure or treatment available given the intentionally incompetent manner this is being dealt with. I agree with your preps, but don't forget the Melatonin I must admit the the appearance of such incompetence has most likely been carefully orchestrated. [link to onlinelibrary.wiley.com] Courage forges a path through all obstacles, while fear is the obstruction of all dreams. The only way that anyone gets something for nothing, is that someone else has given up something for nothing. |
| Anonymous Coward User ID: 5411475 United States10/04/2014 01:41 AM Report Abusive Post Report Copyright Violation | Thanks, and thanks for the pin. Quoting: emerald eye I just don't want people to be caught off guard, believing the "party line" and not protecting themselves properly. The CDC can legally say the things that they are saying about transmission, because they are basing it upon the transmission epidemiology that has been observed in Africa, so essentially they are telling somewhat of the truth. The problem is that the epidemiology in the lab may be different, and that lab environment seems to coincide more closely to hospitals, planes, office buildings, subways, and the northern hemisphere in winter. A new epidemiology may evolve due to a new environment, and I don't think that we can necessarily extrapolate the African epidemiology for the Northern Hemisphere entering fall and winter. We are safer extrapolating the lab data and being abundantly cautious, rather that optimistically careless. Regards to all and stay safe. PS I am sorry there was so much text, but I could explain it in a credible way without it. Dunno about you but a stash of proper reverse transcriptase inhibitor, in addition to endorphin amplification regimen and some extra vitC and multivits are about all you can do besides oral k replacement solution, d5lr iv and a house full of uv lamps and cases of pool bleach along with easily prepared food stored at home would seem to be words to the wise. It should go without saying that there is a reliable cure or treatment available given the intentionally incompetent manner this is being dealt with. I agree with your preps, but don't forget the Melatonin I must admit the the appearance of such incompetence has most likely been carefully orchestrated. [link to onlinelibrary.wiley.com] Id need a reasonable mechanism before bothering with melatonin. Ive been able to significantly soften expression almost to the description of cure of herpes, shingles and soft tissue sarcoma with endorphin manipulation alone in man and beast. |
| Eleven-15
User ID: 63469604 United States10/04/2014 01:43 AM  Report Abusive Post Report Copyright Violation | |
| Term Limits
User ID: 51319803 United States10/04/2014 01:51 AM Report Abusive Post Report Copyright Violation | The bullshit they keep repeating that "the virus is only transmit table when the infected are showing symptoms, that there is ZERO chance of contracting it from someone not visibly ill" is just that, bullshit. Sure, they are more infectious because the virus count is higher and there is more opportunity for aerosol transmission via coughing, sneezing, projectile vomiting, etc... But the infected are just that, and transmission can occur at any phase. It's disgusting to hear these bureaucratic assholes parrot the same crap, like everything else in their delusional world they stick to the mantra that if they repeat it often enough people will believe them. Meanwhile common sense is kicked to the curb and left to the "crazy and paranoid." If a virus is trapped in a tropical climate but thrives in cool, dark caves with lower humidity, and nature keeps it in check through environmental conditions... And when it does outbreak in an isolated population where the inhabitants live in small villages, travel slowly by foot and come in contact with very few people before they are too sick or to dead to continue acting as host... Those are perfectly sound explanations for how/why outbreaks are so small and confined. Introduce a predator into a new environment, one more like the preferred natural conditions and among people who live in large cities, travel long distances in short periods of time, and come in contact with exponentially larger numbers of people.... Well, it would seem the first world temperate climate headed into fall would be far more conducive to a huge epidemic than in some 3rd world sub-Saharan, shithole village. Term Limits for EVERY elected and appointed office. An end to career politicians for real change. |
| Anonymous Coward User ID: 47585876 United States10/04/2014 01:52 AM Report Abusive Post Report Copyright Violation | |
| emerald eye
(OP) Keeping an "eye out" for the truth. User ID: 62374069 United States10/04/2014 02:09 AM Report Abusive Post Report Copyright Violation | The bullshit they keep repeating that "the virus is only transmit table when the infected are showing symptoms, that there is ZERO chance of contracting it from someone not visibly ill" is just that, bullshit. Quoting: Term Limits Sure, they are more infectious because the virus count is higher and there is more opportunity for aerosol transmission via coughing, sneezing, projectile vomiting, etc... But the infected are just that, and transmission can occur at any phase. It's disgusting to hear these bureaucratic assholes parrot the same crap, like everything else in their delusional world they stick to the mantra that if they repeat it often enough people will believe them. Meanwhile common sense is kicked to the curb and left to the "crazy and paranoid." If a virus is trapped in a tropical climate but thrives in cool, dark caves with lower humidity, and nature keeps it in check through environmental conditions... And when it does outbreak in an isolated population where the inhabitants live in small villages, travel slowly by foot and come in contact with very few people before they are too sick or to dead to continue acting as host... Those are perfectly sound explanations for how/why outbreaks are so small and confined. Introduce a predator into a new environment, one more like the preferred natural conditions and among people who live in large cities, travel long distances in short periods of time, and come in contact with exponentially larger numbers of people.... Well, it would seem the first world temperate climate headed into fall would be far more conducive to a huge epidemic than in some 3rd world sub-Saharan, shithole village. Exactly! Thanks for "getting it" Good night everyone, I am not ducking out on the thread, I just cannot keep my eyes open anymore.  Courage forges a path through all obstacles, while fear is the obstruction of all dreams. The only way that anyone gets something for nothing, is that someone else has given up something for nothing. |
| Anonymous Coward User ID: 63591617 United States10/04/2014 02:10 AM Report Abusive Post Report Copyright Violation | |
| Anonymous Coward User ID: 5411475 United States10/04/2014 02:25 AM Report Abusive Post Report Copyright Violation | Thanks, and thanks for the pin. Quoting: emerald eye I just don't want people to be caught off guard, believing the "party line" and not protecting themselves properly. The CDC can legally say the things that they are saying about transmission, because they are basing it upon the transmission epidemiology that has been observed in Africa, so essentially they are telling somewhat of the truth. The problem is that the epidemiology in the lab may be different, and that lab environment seems to coincide more closely to hospitals, planes, office buildings, subways, and the northern hemisphere in winter. A new epidemiology may evolve due to a new environment, and I don't think that we can necessarily extrapolate the African epidemiology for the Northern Hemisphere entering fall and winter. We are safer extrapolating the lab data and being abundantly cautious, rather that optimistically careless. Regards to all and stay safe. PS I am sorry there was so much text, but I could explain it in a credible way without it. Dunno about you but a stash of proper reverse transcriptase inhibitor, in addition to endorphin amplification regimen and some extra vitC and multivits are about all you can do besides oral k replacement solution, d5lr iv and a house full of uv lamps and cases of pool bleach along with easily prepared food stored at home would seem to be words to the wise. It should go without saying that there is a reliable cure or treatment available given the intentionally incompetent manner this is being dealt with. I agree with your preps, but don't forget the Melatonin I must admit the the appearance of such incompetence has most likely been carefully orchestrated. [link to onlinelibrary.wiley.com] Thanks for the artical cite. I found it not so great and more than a little too speculative and tenously supported. that said oral dosing is unpredictable to my recollection and its specific target receptot remains unknown. Moreover the implication of a central role in treatment of sepsis borders on intentionally deceptive when at best it would be in a relatively perioheral role when compared to antibiotics and electrolyte and acidosis management. Its action as an immunomoderator is speculative at best again without designation of a target recepter. That said, as any real treatments are likely to be kept secret for high party officials as their personal insurance policy, melatonin is easy and cheap compared to TNF blockers or even reverse transcriptase inhibitors Im of the opinion that prevention of DIC and cytokine storm is likely to be more a function of controlling viral proliferation and total viral load where inhibiting replication will be a better method than attempting controls further downstream in the chain of events. |
| Anonymous Coward User ID: 62937365 Canada10/04/2014 02:36 AM Report Abusive Post Report Copyright Violation | I'm really IMPRESSED with the research it took to put this post together. OUTSTANDING!! Quoting: IM YOUR HUCKLEBERRY I do believe you can find this info on wikipedia. Reston was Ebola Zaire, but since the virus morphed and it happened in Reston VA USA, thats the name. At least that was my take on it. |
| emerald eye
(OP) Keeping an "eye out" for the truth. User ID: 62374069 United States10/04/2014 02:54 AM Report Abusive Post Report Copyright Violation | Thanks, and thanks for the pin. Quoting: emerald eye I just don't want people to be caught off guard, believing the "party line" and not protecting themselves properly. The CDC can legally say the things that they are saying about transmission, because they are basing it upon the transmission epidemiology that has been observed in Africa, so essentially they are telling somewhat of the truth. The problem is that the epidemiology in the lab may be different, and that lab environment seems to coincide more closely to hospitals, planes, office buildings, subways, and the northern hemisphere in winter. A new epidemiology may evolve due to a new environment, and I don't think that we can necessarily extrapolate the African epidemiology for the Northern Hemisphere entering fall and winter. We are safer extrapolating the lab data and being abundantly cautious, rather that optimistically careless. Regards to all and stay safe. PS I am sorry there was so much text, but I could explain it in a credible way without it. Dunno about you but a stash of proper reverse transcriptase inhibitor, in addition to endorphin amplification regimen and some extra vitC and multivits are about all you can do besides oral k replacement solution, d5lr iv and a house full of uv lamps and cases of pool bleach along with easily prepared food stored at home would seem to be words to the wise. It should go without saying that there is a reliable cure or treatment available given the intentionally incompetent manner this is being dealt with. I agree with your preps, but don't forget the Melatonin I must admit the the appearance of such incompetence has most likely been carefully orchestrated. [link to onlinelibrary.wiley.com] Thanks for the artical cite. I found it not so great and more than a little too speculative and tenously supported. that said oral dosing is unpredictable to my recollection and its specific target receptot remains unknown. Moreover the implication of a central role in treatment of sepsis borders on intentionally deceptive when at best it would be in a relatively perioheral role when compared to antibiotics and electrolyte and acidosis management. Its action as an immunomoderator is speculative at best again without designation of a target recepter. That said, as any real treatments are likely to be kept secret for high party officials as their personal insurance policy, melatonin is easy and cheap compared to TNF blockers or even reverse transcriptase inhibitors Im of the opinion that prevention of DIC and cytokine storm is likely to be more a function of controlling viral proliferation and total viral load where inhibiting replication will be a better method than attempting controls further downstream in the chain of events. I provided the Melatonin article because, although not perfect, at least it is a scientific paper published by a university, and Melatonin is inexpensive, easily obtainable, and has a good safety profile. You are correct, that by the time the vascular instability and DIC appear, the disease is usually fatal. If Melatonin, however, might help to prevent inflammatory changes, prevent vascular instability, and DIC, it might be worthwhile, especially with a reasonable safety profile. One of the articles I looked at a while back showed that two of the characteristics of those who survived were that they had an initial robust immune response, and they did not develop severe cytokine storm. As with many other serious illness, preventing cytokine storm seems to be very important. I am too sleepy right now to find the article, but I promise to follow up on this tomorrow. Many people here are trying to figure out a basic game plan of the best steps to take to avoid this infection, present a robust immune response if exposed, and avoid cytokine storm, especially if the health care system becomes overwhelmed and ineffective. My intent is to try to provide some reasonable basic guidelines, and I welcome input from anyone as long as what they present meets the criteria of relative safety, reasonable availability, and also has some scientific evidence in support of its efficacy. Good night, and I promise to follow up on this tomorrow, even if the thread is not pinned. Last Edited by emerald eye on 10/04/2014 02:57 AM Courage forges a path through all obstacles, while fear is the obstruction of all dreams. The only way that anyone gets something for nothing, is that someone else has given up something for nothing. |
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| twortle
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For later
